Evidence map›Paper›PMID 41112454›Full record

ArticleJTCVS techniques2025

Should minimally invasive surgery be the standard approach for early-stage thymoma? A 20-year experience.

Oliver J Harrison, Kay See Tan, Joseph Dycoco, Katherine Gray, Smita Sihag, Daniela Molena, Matthew Bott, Gaetano Rocco, James Isbell, Prasad Adusumilli and 5 more

Abstract read
In one paragraph

Article in JTCVS techniques, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Oliver J HarrisonDepartment of Thoracic Surgery, Memorial Sloan Kettering Cancer Center, New York, NY.
Kay See TanDepartment of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY.
Joseph DycocoDepartment of Thoracic Surgery, Memorial Sloan Kettering Cancer Center, New York, NY.
Katherine GrayDepartment of Thoracic Surgery, Memorial Sloan Kettering Cancer Center, New York, NY.
Smita SihagDepartment of Thoracic Surgery, Memorial Sloan Kettering Cancer Center, New York, NY.
Daniela MolenaDepartment of Thoracic Surgery, Memorial Sloan Kettering Cancer Center, New York, NY.
Matthew BottDepartment of Thoracic Surgery, Memorial Sloan Kettering Cancer Center, New York, NY.
Gaetano RoccoDepartment of Thoracic Surgery, Memorial Sloan Kettering Cancer Center, New York, NY.
James IsbellDepartment of Thoracic Surgery, Memorial Sloan Kettering Cancer Center, New York, NY.
Prasad AdusumilliDepartment of Thoracic Surgery, Memorial Sloan Kettering Cancer Center, New York, NY.
David JonesDepartment of Thoracic Surgery, Memorial Sloan Kettering Cancer Center, New York, NY.
James HuangDepartment of Thoracic Surgery, Memorial Sloan Kettering Cancer Center, New York, NY.
Valerie RuschDepartment of Thoracic Surgery, Memorial Sloan Kettering Cancer Center, New York, NY.
Manjit BainsDepartment of Thoracic Surgery, Memorial Sloan Kettering Cancer Center, New York, NY.
Bernard ParkDepartment of Thoracic Surgery, Memorial Sloan Kettering Cancer Center, New York, NY.

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4M
NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

Background: Minimally invasive surgery (MIS) has become the prevailing technique for resecting early-stage thymoma; however, studies evaluating the oncologic impact of this evolution are lacking. This study aimed to characterize the transition from open surgery to MIS and to evaluate outcomes. Methods: This was a retrospective, single-institution review of resections performed for pathologic TNM stage I-II thymomas between January 2000 and September 2023. The relationships between factors and recurrence were quantified using competing risk regression before and after applying overlap propensity score weights. Results: A total of 296 patients were identified, including 118 who underwent open surgery and 178 who underwent MIS (25 with video-assisted thoracic surgery and 153 with robotic-assisted thoracic surgery). Open surgery composed the vast majority of cases (92.3%) performed between 2000 and 2009, compared to 26.7% between 2010 and 2023 ( Conclusions: MIS has become the principal approach for resecting early-stage thymoma over the last 2 decades. MIS is associated with a lower complication rate and shorter LOS but may be associated with a higher risk of recurrence in certain situations. Larger studies to evaluate the appropriate role of MIS are warranted.

Indexed as

minimally invasive surgeryopen surgeryrecurrencerobot-assisted surgerysurgical outcomesthymoma

Identifiers

PMID41112454
PMCPMC12529688

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.