ArticleNMC case report journal2025
Dural Marginal Zone B Cell Lymphoma Presenting as a Non-traumatic Acute Epidural Hematoma: A Case Report.
Article in NMC case report journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Marginal zone B cell lymphoma, which can sometimes resemble a meningioma, originates in the dura mater. Reports of marginal zone B cell lymphoma complicated by intracranial hemorrhage are rare. There have been five reported cases of dural marginal zone B cell lymphoma complicated by acute subdural hematoma. To our knowledge, this is the first reported case of dural marginal zone B cell lymphoma diagnosed at the onset of a non-traumatic acute epidural hematoma. A 74-year-old man presented to our hospital with complaints of right hemiparesis without a history of head injury. He was diagnosed with left acute epidural hematoma based on the results of a computed tomography scan of the head; however, his serum soluble interleukin-2 receptor level was elevated (3,520 U/mL), and whole-body contrast-enhanced computed tomography revealed intra-abdominal and bilateral inguinal lymphadenopathy. Contrast-enhanced magnetic resonance imaging of the head revealed a well-enhanced, thickened dura mater with an acute epidural hematoma. The patient underwent a biopsy of the thickened dura mater and a hematoma removal, which on histopathology revealed dural marginal zone B cell lymphoma, as did a biopsy of an inguinal lymph node. After chemotherapy, the thickened dura mater shrank, and the marginal zone B cell lymphoma lesions showed remission. However, the mechanism underlying acute epidural hematoma in the dural marginal zone B cell lymphoma remains unclear. This case report provides new insights into dural marginal zone B cell lymphoma as a cause of non-traumatic acute epidural hematoma.
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