Evidence map›Paper›PMID 41112377›Full record

ArticleSurgical neurology international2025

Effect of rocuronium-sugammadex versus cisatracurium on motor evoked potentials (RECAP-MEP)-A randomized controlled trial.

Sapna Suresh, Ajay Prasad Hrishi, Jithendra Thiruvathra, Ganesh Divakar

Abstract read
In one paragraph

Article in Surgical neurology international, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Author's comments on RECAP-MEP trial.Surgical neurology international · 2026
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Sapna SureshAnesthesia and Critical Care, Aster Medicity, Kochi, Kerala, India.
Ajay Prasad HrishiNeuroanesthesia and Critical Care, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Trivandrum, Kerala, India.
Jithendra ThiruvathraAnesthesia and Critical Care, Aster Medicity, Kochi, Kerala, India.
Ganesh DivakarDepartment of Neurosurgery, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Trivandrum, Kerala, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Transcranial motor-evoked potentials (TcMEPs) are essential for monitoring spinal cord integrity during spine surgery, but are highly sensitive to neuromuscular blocking agents. This study compared the effects of rocuronium reversed with sugammadex versus cisatracurium on TcMEP amplitude and recovery characteristics during thoracic and lumbar spine surgery. Methods: A double-blinded, randomized controlled trial was conducted in 60 patients undergoing elective spine surgery. Participants were randomized to receive either rocuronium 0.6 mg/kg with sugammadex reversal (Group R, Results: Group R demonstrated significantly higher MEP amplitudes and shorter MEP latency at all time points from baseline till 30 min as compared to group C ( Conclusion: At similar TOF ratios, sugammadex-facilitated reversal of rocuronium results in superior quality of MEP parameters, such as higher MEP amplitude and shorter MEP latency, with no significant difference in adverse movements compared to single-dose cisatracurium.

Indexed as

CisatracuriumMotor evoked potentialsRocuroniumSpine surgerySugammadex

Identifiers

PMID41112377
PMCPMC12530776

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.