Evidence map›Paper›PMID 41112261›Full record

ArticleFrontiers in immunology2025

Gene variants of glucocorticoid activation pathways and the outcomes of patients with Takayasu arteritis - a retrospective cohort study.

Faustino Peron Filho, Andressa de Souza Moreira, Eduarda Bonelli Zarur, Gerson Dierley Keppeke, Alexandre Wagner Silva de Souza

Abstract read
In one paragraph

Article in Frontiers in immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Faustino Peron FilhoRheumatology Division, Department of Medicine, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, Brazil.
Andressa de Souza MoreiraRheumatology Division, Department of Medicine, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, Brazil.
Eduarda Bonelli ZarurRheumatology Division, Department of Medicine, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, Brazil.
Gerson Dierley KeppekeRheumatology Division, Department of Medicine, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, Brazil.
Alexandre Wagner Silva de SouzaRheumatology Division, Department of Medicine, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: This study aims to evaluate the influence of polymorphisms of the Methods: A retrospective cohort study including 81 TAK patients was carried out. Polymorphisms of the genes Results: The polymorphism 9β of the Conclusion: Worsening glucose tolerance and the carriage of 9β of the

Indexed as

GlucocorticoidsPolymorphism, Single NucleotideReceptors, GlucocorticoidTakayasu Arteritis11-beta-Hydroxysteroid Dehydrogenase Type 1AdolescentAdultFemaleGenetic Predisposition to DiseaseGenotypeHaplotypesHumansMaleMiddle AgedRetrospective StudiesTacrolimus Binding Protein 511-beta-Hydroxysteroid Dehydrogenase Type 1GlucocorticoidsHSD11B1 protein, humanNR3C1 protein, humanReceptors, GlucocorticoidTacrolimus Binding Protein 5Tacrolimus Binding Proteinsdrug toxicitygenetic studiesglucocorticoidssingle nucleotide polymorphismTakayasu arteritis

Identifiers

PMID41112261
PMCPMC12528102

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.