Evidence map›Paper›PMID 41112204›Full record

ArticleNEJM AI2025

The use of artificial intelligence for cancer therapeutic decision-making.

Olivier Elemento, Sean Khozin, Cora N Sternberg

Abstract read
In one paragraph

Article in NEJM AI, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
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  5. Article
  6. Article
  7. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Olivier ElementoEnglander Institute for Precision Medicine, Weill Cornell Medicine.
Sean KhozinCEO Roundtable on Cancer.
Cora N SternbergEnglander Institute for Precision Medicine, Weill Cornell Medicine.

Funding

Clinical and Translational Science AwardUL1TR001873 · NCATS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI REILLY, MUREDACH P · 2016 to 2025
$99.0M
Disparities in COVID Disease Severity and Outcomes in New York CityUL1TR002384 · NCATS · WEILL MEDICAL COLL OF CORNELL UNIV · PI JULIANNE L IMPERATO-MCGINLEY · 2017 to 2026
$86.2M
NCATS NIH HHS UL1 TR001873NCATS NIH HHS UL1 TR002384
6 · The paper itself

Abstract

Artificial intelligence (AI) has the potential to transform cancer therapeutic decision-making by improving diagnostics and personalizing treatments. This review explores the current and future impact of AI in oncology, focusing on its applications in radiology, pathology, and the potential of Large Language Models (LLMs) in treatment selection. Despite significant advancements, AI integration into clinical workflows is limited due to challenges like data quality, model accuracy, and lack of validation through clinical trials. We propose key strategies to address these challenges, including developing robust multi-center datasets, promoting practical AI model development, researching workflow integration and human-AI collaboration, leveraging lessons from AI in medical imaging, establishing evaluation guidelines, and incentivizing prospective clinical trials. By implementing these strategies, AI can significantly enhance cancer care and patient outcomes, paving the way for its effective integration into oncology practice.

Identifiers

PMID41112204
PMCPMC12530061

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.