ReviewArrhythmia & electrophysiology review2025
Pulmonary Vein Isolation: Cornerstone of Atrial Fibrillation Ablation and Its Evolving Challenges. A Critical Review.
Review in Arrhythmia & electrophysiology review, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- The ablation of the low-voltage area in the left atrial anterior wall caused by mechanical compression from the ascending aorta: a potential strategy for terminating atrial fibrillation.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
AF is the most common cardiac arrhythmia, affecting millions worldwide. Catheter ablation has evolved into a cornerstone treatment for AF, offering better rhythm control and symptom relief than antiarrhythmic medications in selected patients. Over the past few decades, AF ablation has evolved significantly. Initially, right atrial approaches were explored before shifting to the left atrium, with pulmonary vein isolation emerging as the principal strategy. Attempts at substrate modification, including complex fractionated atrial electrograms ablation, linear lesions and rotorbased approaches, have been explored, but yielded inconsistent results. Recent studies reaffirm pulmonary vein isolation as the cornerstone of AF ablation. This review critically evaluates the evolution of AF ablation, the scientific rationale behind different strategies, technological advancements and future directions in the field.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.