ArticleNeurotrauma reports2025
Identifying Clinical Predictors of Raised Intracranial Pressure in Pediatric Traumatic Brain Injury-A Multinational Initiative.
Article in Neurotrauma reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Use of the intracranial pressure (ICP) monitor in pediatric traumatic brain injury (TBI) remains variable. Clinical prediction models of raised ICP have been reported in adult TBI but have not been validated in pediatric TBI. We aimed to investigate clinical predictors and derive a prediction model for raised ICP in pediatric patients with TBI. A real-world observational study was conducted among pediatric intensive care units from the Pediatric Acute & Critical Care Medicine Asian Network and Red Colaborativa Pediátrica de Latinoamerica. Children <18 years with moderate-to-severe TBI and who were hospitalized between 2014 and 2022 were included. We defined raised ICP as >20 mmHg. Multivariable logistic regression models were built to identify significant predictors for raised ICP, and performance was assessed using the area under the receiver operating characteristic curve (AUC). Among 706 pediatric patients, only 151 (21.4%) had ICP monitoring, and 75 (49.7%) were confirmed to have raised ICP. Mortality was 13.2%, 8.0%, and 4.0% for patients who did not receive ICP monitoring, those with raised ICP, and those with normal ICP, respectively (
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