Evidence map›Paper›PMID 41112050›Full record

ArticleiMeta2025

Shaping the future of probiotics, live biotherapeutic products, and fecal microbiota transplantation: 30 scientific recommendations from the CHINAGUT Conference.

Weihong Wang, Nan Bu, Hailong Cao, Ning Chen, Wei Chen, Lei Cheng, Bota Cui, Lei Dai, Huiying Gao, Meng Guo and 53 more

Abstract readEditorial
In one paragraph

Article in iMeta, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Potential and Challenges ofFoods (Basel, Switzerland) · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

63 authors.

Weihong WangDepartment of Microbiota Medicine & Medical Center for Digestive Diseases The Second Affiliated Hospital of Nanjing Medical University Nanjing China.ORCID https://orcid.org/0000-0002-8256-2183
Nan BuDepartment of Gastroenterology Jiamusi Hospital of Traditional Chinese Medicine Jiamusi China.
Hailong CaoDepartment of Gastroenterology and Hepatology, Tianjin Medical University General Hospital, National Key Clinical Specialty, Tianjin Institute of Digestive Diseases Tianjin Key Laboratory of Digestive Diseases Tianjin China.
Ning ChenDepartment of Gastroenterology Peking University People's Hospital Beijing China.
Wei ChenSchool of Food Science and Technology Jiangnan University Wuxi China.
Lei ChengKey Laboratory of Development and Application of Rural Renewable Energy Biogas Institute of Ministry of Agriculture and Rural Affairs Chengdu China.
Bota CuiDepartment of Microbiota Medicine & Medical Center for Digestive Diseases The Second Affiliated Hospital of Nanjing Medical University Nanjing China.
Lei DaiCAS Key Laboratory of Quantitative Engineering Biology, Shenzhen Institute of Synthetic Biology, Shenzhen Institute of Advanced Technology Chinese Academy of Sciences Shenzhen China.
Huiying GaoDepartment of Gastroenterology Jingxing County Hospital Shijiazhuang China.
Meng GuoState Key Laboratory of lmmune Response and lmmunotherapy, Division of Life Sciences and Medicine University of Science and Technology of China Hefei China.
Xingxiang HeDepartment of Gastroenterology The First Affiliated Hospital of Guangdong Pharmaceutical University Guangzhou China.
Jia HuDepartment of Gastroenterology The Affiliated Hospital of Jiangxi University of Traditional Chinese Medicine Nanchang China.
Changtao JiangDepartment of Physiology and Pathophysiology, School of Basic Medical Sciences, State Key Laboratory of Female Fertility Promotion Center for Reproductive Medicine, Peking University Beijing China.
Xianzhi JiangMoonBiotech Guangzhou China.
Jingnan LiDepartment of Gastroenterology Peking Union Medical College Hospital Beijing China.
Ping LiCollege of Food Science and Biotechnology Zhejiang Gongshang University Hangzhou China.
Wei LiCollege of Food Science and Technology Nanjing Agricultural University Nanjing China.
Weiwei LiaoDepartment of Gastroenterology, Capital Center for Children's Health Capital Medical University Beijing China.
Hongwei LiuState Key Laboratory of Mycology, Institute of Microbiology Chinese Academy of Sciences Beijing China.ORCID https://orcid.org/0000-0001-6471-131X
Jingmei LiuDepartment of Gastroenterology, Shanxi Province Cancer Hospital/Shanxi Hospital Affiliated to Cancer Hospital Chinese Academy of Medical Sciences/Cancer Hospital Affiliated to Shanxi Medical University Taiyuan China.
Ling LiuDepartment of Gastroenterology and Hepatology, West China Hospital Sichuan University Chengdu China.
Shuangjiang LiuState Key Laboratory of Mycology, Institute of Microbiology Chinese Academy of Sciences Beijing China.ORCID https://orcid.org/0000-0002-7585-310X
Xingyin LiuDepartment of Biochemistry, SUSTech Homeostatic Medicine Institute, School of Medicine Southern University of Science and Technology Shenzhen Guangdong China.
Muhan LvDepartment of Gastroenterology The Affiliated Hospital of Southwest Medical University Luzhou China.
Yonghui MaCentre for Bioethics Xiamen University Xiamen China.ORCID https://orcid.org/0000-0001-5787-8445
Chaoxin ManCollege of Food Science Northeast Agricultural University Harbin China.
Zheshun PiDepartment of Microbiota Medicine & Medical Center for Digestive Diseases The Second Affiliated Hospital of Nanjing Medical University Nanjing China.ORCID https://orcid.org/0009-0005-2404-4475
Qian RenDepartment of Gastroenterology The First Hospital of Lanzhou University Lanzhou China.
Lixuan SangDepartment of Gastroenterology Shengjing Hospital of China Medical University Shenyang China.
Zhihong SunDairy College of Inner Mongolia Agricultural University Inner Mongolia Agricultural University Hohhot China.ORCID https://orcid.org/0000-0002-7605-2048
Huayi SuoCollege of Food Science Southwest University Chongqing China.
Yan TanXBIOME Shenzhen China.
Wanyin TaoiBIOME Hefei China.
Guangqiang WangSchool of Health Science and Engineering University of Shanghai for Science and Technology Shanghai China.
Jun WangCAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology Chinese Academy of Sciences Beijing China.
Liangjing WangDepartment of Gastroenterology Second Affiliated Hospital of Zhejiang University School of Medicine Hangzhou China.
Xin WangNingbo R-Institute of Science Communication Ningbo China.
Xin WangDepartment of Gastroenterology, Tangdu Hospital Air Force Medical University Xi'an China.
Ye WangZYBio Guangzhou China.
Kaichun WuDepartment of Gastroenterology, Xijing Hospital Air Force Medical University Xi'an China.
Rina WuCollege of Food Science Shenyang Agricultural University Shenyang China.ORCID https://orcid.org/0000-0002-5846-0013
Zhen WuCollege of Food and Pharmaceutical Sciences Ningbo University Ningbo China.
Xiang XiaoSchool of Food and Biological Engineering Jiangsu University Zhenjiang China.
Bin XiangCOMMBIO Shanghai China.
Song YangDepartment of Hepatology, Beijing Ditan Hospital Capital Medical University Beijing China.
Huaxi YiCollege of Food Science and Engineering Ocean University of China Qingdao China.
Honho YuDepartment of Gastroenterology and Hepatology Kiang Wu Hospital Macao SAR China.
Jun YuInstitute of Digestive Disease and The Department of Medicine and Therapeutics, State Key Laboratory of Digestive Disease, Li Ka Shing Institute of Health Sciences, CUHK Shenzhen Research Institute The Chinese University of Hong Kong Hong Kong China.ORCID https://orcid.org/0000-0001-5008-2153
Yue ZengDepartment of Gastroenterology, Shanghai General Hospital Shanghai Jiao Tong University School of Medicine Shanghai China.
Huihong ZhaiDepartment of Gastroenterology, Xuanwu Hospital Capital Medical University Beijing China.
Qixiao ZhaiSchool of Food Science and Technology Jiangnan University Wuxi China.
Chenhong ZhangState Key Laboratory of Microbial Metabolism, School of Life Sciences and Biotechnology Shanghai Jiao Tong University Shanghai China.
Guohua ZhangSchool of Life Science Shanxi University Taiyuan China.
Jiachao ZhangSchool of Food Science and Engineering Hainan University Haikou China.
Wenyi ZhangCollege of Food Science and Engineering Inner Mongolia Agricultural University Hohhot China.ORCID https://orcid.org/0000-0001-5530-4210
Fangqing ZhaoBeijing Institutes of Life Science Chinese Academy of Sciences Beijing China.
Liang ZhaoCollege of Food Science and Nutritional Engineering China Agricultural University Beijing China.
Hongwei ZhouDivision of Laboratory Medicine, Zhujiang Hospital Southern Medical University Guangzhou China.
Li ZhuDepartment of Pediatric Gastroenterology, Maternal and Child Health Hospital of Guiyang Province Guiyang China.
Canhui LanNingbo R-Institute of Science Communication Ningbo China.
Heping ZhangCollege of Food Science and Engineering Inner Mongolia Agricultural University Hohhot China.
Shu ZhuState Key Laboratory of lmmune Response and lmmunotherapy, Division of Life Sciences and Medicine University of Science and Technology of China Hefei China.
Faming ZhangDepartment of Microbiota Medicine & Medical Center for Digestive Diseases The Second Affiliated Hospital of Nanjing Medical University Nanjing China.ORCID https://orcid.org/0000-0003-4157-1144

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The 2025 CHINAGUT Conference has assembled a panel of 63 experts (30 scientists, 26 physicians, and 7 corporate R&D personnel) collaborated in three groups to present 30 scientific recommendations to advance probiotics, live biotherapeutic products, and fecal microbiota transplantation, addressing key issues on standardization, translation, supervision, regulation, and regulatory harmonization. These interdisciplinary guidelines aim to synthesize cutting-edge knowledge and practical needs to transform microbiota-based treatments from applications into precision-driven medical solutions, and serve as reference by scientific researchers, medical educators, pharmaceutical enterprises, clinicians, food and drug administrations, policymakers, and patients.

Identifiers

PMID41112050
PMCPMC12527994

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.