Evidence map›Paper›PMID 41111915›Full record

ArticleiScience2025

Molecularly imprinted polypyrrole-based POF dual sensor for dopamine detection exploiting plasmonic and voltammetric methods.

Alessandra Cutaia, Rosalba Pitruzzella, Debora Bencivenga, Adriana Borriello, Chiara Marzano, Nunzio Cennamo, Giancarla Alberti

Abstract read
In one paragraph

Article in iScience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Alessandra CutaiaDepartment of Chemistry, University of Pavia, Via Taramelli n.12, 27100 Pavia, Italy.
Rosalba PitruzzellaDepartment of Engineering, University of Campania Luigi Vanvitelli, Via Roma n.29, 81031 Aversa, Italy.
Debora BencivengaDepartment of Precision Medicine, University of Campania "Luigi Vanvitelli", via L. De Crecchio n. 7, 80138 Naples, Italy.
Adriana BorrielloDepartment of Precision Medicine, University of Campania "Luigi Vanvitelli", via L. De Crecchio n. 7, 80138 Naples, Italy.
Chiara MarzanoDepartment of Engineering, University of Campania Luigi Vanvitelli, Via Roma n.29, 81031 Aversa, Italy.
Nunzio CennamoDepartment of Engineering, University of Campania Luigi Vanvitelli, Via Roma n.29, 81031 Aversa, Italy.
Giancarla AlbertiDepartment of Chemistry, University of Pavia, Via Taramelli n.12, 27100 Pavia, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This work introduces a dual-mode chemical sensor for the detection of dopamine. It exploits an electropolymerized molecularly imprinted polypyrrole (eMIP) on a surface plasmon resonance (SPR) D-shaped plastic optical fiber (POF) platform, where the gold nanofilm serves as both a plasmonic surface and a working electrode within a voltammetric cell. The eMIP deposition and template extraction were monitored in real-time by the variation in plasmonic resonance wavelength. A custom cell enables the detection of dopamine via SPR or differential pulse voltammetry (DPV), depending on the sample matrix and analyte concentration. The sensor's performance was thoroughly evaluated using both transduction methods, showing excellent sensitivity across a broad range, from picomolar to micromolar levels. Real biological samples, such as blood (analyzed via SPR) and urine (via DPV), were tested, highlighting the sensor's strong potential as a versatile and highly sensitive hybrid tool for dopamine monitoring.

Indexed as

BiotechnologyChemistryMolecular imprinted techniqueSensor

Identifiers

PMID41111915
PMCPMC12529502

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.