Observational studyGlobal heart2025
Body Mass Index and the Risk of Hypertension-Diabetes Comorbidity in Elderly Population: A Prospective Cohort in China.
Observational study in Global heart, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Multi-horizon machine learning for population-level hypertension risk stratification in the UK Biobank.European heart journal. Digital health · 2026Article
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4 authors.
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Abstract
Background: Body mass index (BMI) is closely linked to hypertension and diabetes mellitus (DM). However, the association between BMI and hypertension-diabetes comorbidity in elderly population of China remains uncertain. Methods: This cohort study was conducted based on a prospective database of Chinese Longitudinal Healthy Longevity Survey (CLHLS). The primary outcome was hypertension-diabetes comorbidity. The secondary outcomes included hypertension and DM. BMI was categorized into four groups according to Chinese guidelines: underweight (BMI < 18.5 kg/m Results: The final analysis included 5,342 individuals for hypertension, 6,335 for DM, and 6,414 for hypertension-diabetes comorbidity (all individuals aged 65 years and above). Cox regression analysis of the hypertension-diabetes comorbidity revealed the adjusted hazard ratio (HR) for the underweight group was 0.747 (95% confidence interval [CI], 0.651-0.857), for the overweight group was 1.517 (95% CI, 1.309-1.758), and for the obesity group was 1.620 (95% CI, 1.237-2.121) comparing with normal weight group (reference). When considering BMI as a continuous variable, the adjusted HR was 1.043 (95% CI, 1.029-1.059). Employing a multi-model adjusting strategy based on the directed acyclic graph, the HR for individuals with BMI ≥ 24.0 (versus BMI < 24.0) was 1.486 (95% CI, 1.301-1.698). Restricted cubic splines indicate a positive linear trend between BMI (range in BMI ≥ 24) and the risk of hypertension-diabetes comorbidity. The relationship between BMI and secondary outcomes exhibited results similar to those of the primary outcome.Additionally, compared to the Han ethnic, other ethnic had a significantly lower risk of the primary outcome, with an adjusted HR of 0.334 (95% CI, 0.235-0.475). Similar findings were observed for the secondary outcomes. Conclusions: Increased BMI is significantly associated with a higher risk of hypertension-diabetes comorbidity, hypertension, and DM in elderly population of China. Additionally, Han participants (versus non-Han) have a notably greater risk of developing hypertension-diabetes comorbidity, hypertension, and DM. Greater attention should be paid to obesity in elderly Han Chinese individuals, given its significant associated disease burden.
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