Evidence map›Paper›PMID 41111893›Full record

ArticleFood science & nutrition2025

Tortoise Oligopeptides Augment Cyclophosphamide's Antitumor Activity Through Dual Modulation of Therapeutic Efficacy and Hematologic Toxicity.

Zhuotao Fu, Tian Yu, Cong Meng, Guoni Zhang, Shaojun Huang, Yuping Li, Linchun Fu, Zhitong Deng

Abstract read
In one paragraph

Article in Food science & nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Zhuotao FuThe First Affiliated Hospital of Guangzhou University of Chinese Medicine Guangzhou China.
Tian YuScience and Technology Innovation Center Guangzhou University of Chinese Medicine Guangzhou China.
Cong MengThe Affiliated TCM Hospital of Guangzhou Medical University Guangzhou China.
Guoni ZhangHaikou Hospital of Traditional Chinese Medicine Haikou China.
Shaojun HuangHaikou Hospital of Traditional Chinese Medicine Haikou China.
Yuping LiHaikou Hospital of Traditional Chinese Medicine Haikou China.
Linchun FuScience and Technology Innovation Center Guangzhou University of Chinese Medicine Guangzhou China.
Zhitong DengHaikou Hospital of Traditional Chinese Medicine Haikou China.ORCID https://orcid.org/0000-0002-7014-3643

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cyclophosphamide (CTX) is a widely used chemotherapeutic agent, but its efficacy is often limited by leukopenia, a common adverse effect for which effective preventive strategies are currently lacking. In this study, oligopeptides were prepared from a blend of three edible tortoise species (

Indexed as

diet therapygut microbiotaleukopeniasmall molecule peptidetumorultrafiltration molecular weight peptides

Identifiers

PMID41111893
PMCPMC12531418

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.