Evidence map›Paper›PMID 41111885›Full record

ArticleFood science & nutrition2025

Safety Evaluation of Ultrasonic-Assisted OSA-Modified Tamarind Seed Gum for Food Applications.

Adan Naeem, Rizwana Batool, Mahwash Aziz, Aysha Sameen, Aiza Zafar, Faiza Azmat, Bakhtawar Saleem, Qamar Sajjad, Awais Raza, Agoura Diantom

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In one paragraph

Article in Food science & nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Adan NaeemDepartment of Food Science and Technology Government College Women University Faisalabad Faisalabad Pakistan.
Rizwana BatoolDepartment of Food Science and Technology Government College Women University Faisalabad Faisalabad Pakistan.
Mahwash AzizDepartment of Food Science and Technology Government College Women University Faisalabad Faisalabad Pakistan.
Aysha SameenDepartment of Food Science and Technology Government College Women University Faisalabad Faisalabad Pakistan.
Aiza ZafarDepartment of Food Science and Technology Government College Women University Faisalabad Faisalabad Pakistan.
Faiza AzmatDepartment of Nutritional Sciences and Environmental Design Allama Iqbal Open University Islamabad Pakistan.ORCID https://orcid.org/0000-0002-1014-9074
Bakhtawar SaleemDepartment of Food Science and Technology Government College Women University Faisalabad Faisalabad Pakistan.
Qamar SajjadNational Institute of Food Science and Technology University of Agriculture Faisalabad Faisalabad Pakistan.
Awais RazaUniversity Institute of Diet and Nutritional Sciences The University of Lahore Lahore Pakistan.
Agoura DiantomDepartment of Food Science and Technology Universite de Lomé Lomé Togo.ORCID https://orcid.org/0009-0005-7029-3085

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Evaluating the safety profile of substances used in food products is essential. Ultrasonic-assisted octenyl succinic acid-modified tamarind seed gum (OSA-TSG) has shown potential as an emulsifier and stabilizer in a variety of food applications; however, its safety profile has not yet been thoroughly investigated. In the present study, the acute oral toxicity of both pure tamarind seed gum (TSG) and ultrasonic-assisted OSA-TSG was evaluated in Sprague Dawley rats over 21 days. The purpose of the study was to assess the safety of these gums with respect to potential adverse effects and mortality following a single oral dose of 300 and 2000 mg/kg body weight. Body weight and feed intake were monitored at 0 and 21 days, respectively, and significant effects were observed in the TSG and ultrasonic-assisted OSA-TSG-treated groups compared to the control group. No adverse effects were seen in hematological and biochemical parameters in either treatment group. Furthermore, no macroscopic or histological alterations were found in vital organs (heart, brain, liver, and kidney) upon necropsy that could be attributed to the administration of test substances. In conclusion, both pure and ultrasonic-assisted OSA-TSG exhibited an LD

Indexed as

biochemical parametershematological parameterssafetyTSGultrasonic‐assisted OSA–TSG

Identifiers

PMID41111885
PMCPMC12531413

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.