ArticleCureus2025
Morcellation Efficiency Across Prostate Size Categories in Holmium Laser Enucleation of the Prostate (HoLEP): A Complete-Case Analysis of 255 Consecutive Procedures at a UK Tertiary Centre.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Prostate morcellation devices: a systematic review and meta-analysis of clinical outcomes and efficiency.BJU international · 2026Pooled it
- Prostatic morcellation after HoLEP Enucleation: efficiency and safety of Storz DrillCut vs. Jena Surgical Multicut Solo.The Canadian journal of urology · 2026Observational
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMechanical morcellation is integral to Holmium Laser Enucleation of the Prostate (HoLEP). Understanding how morcellation efficiency varies with gland size can inform list planning, device selection, and safety preparedness.
objectiveTo quantify morcellation efficiency across preoperative prostate size categories and examine its association with gland volume.
methodsWe performed a retrospective, single-centre, complete-case analysis of 255 consecutive HoLEP procedures at a UK tertiary centre (January 2022-January 2025). Preoperative transrectal ultrasound (TRUS) prostate volume was categorised as <80 cc, 80-150 cc, and >150 cc. Morcellation efficiency (g/min) was calculated as enucleated tissue weight divided by morcellation time. Group differences were assessed nonparametrically with Kruskal-Wallis and Bonferroni-adjusted pairwise tests, and the relationship between volume and efficiency was evaluated with Spearman's ρ.
resultsSize distribution was <80 cc 51 (20.0%), 80-150 cc 141 (55.3%), and >150 cc 63 (24.7%). Median morcellation efficiency decreased across categories: 9.02 (IQR 6.37-13.25) vs 8.71 (IQR 6.00-12.21) vs 7.00 g/min (IQR 4.25-9.57) (Kruskal-Wallis H=13.23, p=0.001); pairwise differences were significant for <80 vs >150 (p=0.005) and 80-150 vs >150 (p=0.003), but not <80 vs 80-150 (p>0.999). Efficiency inversely correlated with volume (ρ=-0.26, p<0.001).
conclusionsMorcellation efficiency decreases as glands become very large (>150 cc); anticipating slower retrieval in mega-prostates can guide list composition, staffing, and morcellator/technique choice.
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