Evidence map›Paper›PMID 41111806›Full record

ArticleCureus2025

Association Between Tibial Plateau Fractures and Bone Metabolic Status: A Prospective Observational Study.

Constantinos D Apostolou, Vassiliki Markopoulou, Georgios Chatzipanagiotou, Stefanos Efstathiou, Efstathios Chronopoulos

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Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Constantinos D ApostolouOrthopaedics and Trauma, Evangelismos General Hospital, Athens, GRC.
Vassiliki MarkopoulouOrthopaedics and Trauma, Evangelismos General Hospital, Athens, GRC.
Georgios ChatzipanagiotouOrthopaedics and Trauma, Evangelismos General Hospital, Athens, GRC.
Stefanos EfstathiouOrthopaedics and Trauma, Evangelismos General Hospital, Athens, GRC.
Efstathios ChronopoulosOrthopaedic Surgery, National and Kapodistrian University of Athens, Athens, GRC.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTibial plateau fractures are serious injuries affecting knee function and mobility. While typically associated with high-energy trauma, these fractures are increasingly observed in low-energy mechanisms, particularly among patients with compromised bone health.

objectiveTo investigate the relationship between tibial plateau fractures and bone health parameters, specifically focusing on vitamin D status and bone mineral density, and to determine if fracture classification correlates with metabolic bone disease indicators.

methodsA prospective observational study was conducted over 11 months at Evangelismos General Hospital in Athens, Greece. A total of 45 patients with tibial plateau fractures and 28 control patients with knee contusions were assessed. All participants underwent biochemical testing and dual-energy X-ray absorptiometry (DEXA) scanning. Fractures were divided using the Schatzker classification.

resultsA total of 34 (75.6%) patients with tibial plateau fractures had vitamin D deficiency, and 14 (31.1%) were diagnosed with osteopenia. Osteopenia was significantly more prevalent in low-energy trauma patients (six among nine patients vs. eight among 36 patients in high-energy trauma; 66.7% vs. 22.2%, p = 0.017). However, no statistically significant correlation was found between fracture severity and metabolic markers.

conclusionA substantial proportion of patients with tibial plateau fractures exhibit suboptimal bone health, especially vitamin D deficiency and osteopenia. Routine metabolic screening is recommended, particularly for fractures caused by low-energy mechanisms.

Indexed as

bone density scandual-energy x-ray absorptiometry (dexa)lower extremity traumaosteoporosistibial plateau fracturesvitamin dvitamin d levels (vit d level)

Identifiers

PMID41111806
PMCPMC12530786

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