ArticleCureus2025
Early Serum Calcium Assessment as a Cost-Effective Tool in Risk Stratification of Acute Pancreatitis.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background Acute pancreatitis is a common gastrointestinal emergency that ranges from mild, self-limiting inflammation to severe disease with multi-organ dysfunction and high mortality. Traditional prognostic scoring systems such as Bedside Index for Severity in Acute Pancreatitis (BISAP) and CT Severity Index (CTSI) are useful but often complex. Biochemical markers like serum calcium may provide a simple and accessible alternative for early risk stratification. Objective To evaluate the role of serum calcium as a prognostic marker in patients with acute pancreatitis by assessing its correlation with BISAP score, CTSI, duration of hospital stay, need for surgical intervention, and clinical outcomes, including mortality. Methods This study was conducted over 18 months at a tertiary care center. Fifty adult patients (≥18 years) with newly diagnosed acute pancreatitis were enrolled. Serum calcium levels measured within 24 hours of admission were analyzed in relation to BISAP score, CTSI, hospital stay, and clinical outcomes. Data were analyzed using the chi-square test, independent t-test, and Pearson's correlation. A p-value <0.05 was considered statistically significant. Results The mean age of patients was 37.9 ± 13.05 years, with a male predominance (66%, n = 33). Gallstones (58%, n = 29) were the most common etiology. Hypocalcemia (<8.5 mg/dL) was observed in 58% (n = 29) of patients. The mean duration of hospital stay was 12.64 ± 4.09 days. The overall mortality rate was 18%, with 82% of patients discharged after recovery. Lower calcium levels were significantly associated with higher CTSI grades (p = 0.001), prolonged hospital stay (r = -0.694, p = 0.001), higher BISAP scores (r = -0.684, p = 0.001), and mortality (p = 0.001). Patients requiring surgical intervention also had significantly lower calcium levels (p = 0.005). Conclusion Hypocalcemia is strongly correlated with disease severity, adverse outcomes, and prolonged hospitalization in acute pancreatitis. Early serum calcium measurement within 24 hours of admission may serve as a simple, cost-effective prognostic tool for clinical decision-making.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.