ArticleCureus2025
Late-Onset Isolated Drain Site Metastasis in Colorectal Cancer Managed by a Multidisciplinary Approach.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
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Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Colorectal cancer (CRC) is one of the most common cancers globally and a leading cause of cancer-related deaths. Over the past decade, our understanding of CRC has significantly evolved, particularly in the areas of genomic prognostication and targeted therapies. However, surgical management beyond the initial resection of the primary tumor remains an area of ongoing discussion and research. We report a case of a 51-year-old man with metastatic CRC and liver metastases, treated with right hemicolectomy and chemotherapy, achieving complete remission. Two years later, he developed an isolated subcutaneous recurrence at the prior surgical drain site. Microsatellite instability status changed from primary to recurrent lesions. Surgical resection achieved negative margins, and the patient has since remained disease-free without additional therapy. This rare presentation challenges traditional models of CRC metastasis and highlights the potential role of lymphatic dissemination, tumor dormancy, or surgical seeding.
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Registered trials
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