ArticleCureus2025
Severe Hypokalemic Paralysis Unmasking Renal Tubular Acidosis in a Patient With Sjögren's Syndrome.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Ensemble signal detection reveals target-specific temporal risk of hypokalemia after immune checkpoint inhibition: a translational pharmacology framework.Frontiers in pharmacology · 2026Article
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Hypokalemic periodic paralysis (HPP) is a rare but life-threatening complication in patients with Sjögren's syndrome (SS), often due to distal renal tubular acidosis (RTA) caused by autoimmune-mediated renal damage. We report a case of a woman in her 30s with a history of rheumatoid arthritis and SS who presented with acute, flaccid paralysis secondary to profound hypokalemia from distal RTA, requiring intensive care support. This patient was treated with central potassium and bicarbonate replacement, leading to marked clinical improvement. This report emphasizes the importance of early recognition of HPP as a manifestation of SS-related RTA and underscores why multidisciplinary management and active long-term follow-up are essential to prevent relapse and optimize patient outcomes.
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