Evidence map›Paper›PMID 41111701›Full record

ArticleCureus2025

Beneath the Surface: A Rash That Uncovered Renal Autoimmunity.

Matheus Vasconcelos Goes Mendes, John R Dahl

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Matheus Vasconcelos Goes MendesUnidade de Terapia Intensiva (UTI 4), Hospital Português, Salvador, BRA.
John R DahlDepartment of Internal Medicine, University of South Florida, Tampa, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report the case of a 42-year-old male who presented with a generalized rash, acute kidney injury, anemia, and positive antinuclear antibodies (ANA). Serologic testing revealed elevated anti-double-stranded DNA (dsDNA) levels and hypocomplementemia, raising concern for systemic lupus erythematosus (SLE). Kidney biopsy confirmed Class III (focal proliferative) lupus nephritis according to the International Society of Nephrology/Renal Pathology Society 2003 classification. Immunofluorescence demonstrated full-house staining (positive for IgG, C3, C1q, and light chains) with weaker signals for IgA and IgM. Electron microscopy revealed subepithelial and mesangial electron-dense deposits. Early recognition and timely initiation of immunosuppressive therapy led to clinical improvement and stabilization of renal function.

Indexed as

acute kidney injuryantinuclear antibodygeneralized rashlupus nephritissystemic lupus erythema

Identifiers

PMID41111701
PMCPMC12532274

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.