ArticleCureus2025
A Rare Case of Necrotizing Soft Tissue Infection in the Labium Resulting From Candida glabrata.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
5 authors.
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Abstract
Necrotizing soft tissue infections (NSTIs) are severe infections affecting the skin, subcutaneous, and muscle tissue. Tissue destruction, systemic toxicity, and increased morbidity are usually observed. An aggressive form of NSTI is called Fournier's gangrene: it starts as a necrotizing fasciitis of the perineal and genital area and affects adjacent soft tissue. It exhibits an increased rate of morbidity, thus requiring a high index of clinical suspicion to secure early surgical debridement. A 58-year-old patient presented in the emergency department complaining of pain in the labia majora. Clinical examination revealed tenderness, erythema, edema, and the presence of a large condyloma on the left labium majus. The patient was admitted and was treated with an antibiotic, with no improvement. A crackling sensation of the affected labium was observed on subsequent examination. Imaging revealed signs of necrosis, and NSTI was confirmed. The patient underwent surgical debridement of the perineum along with removal of the condyloma. A vacuum-assisted closure device was used for secondary healing of the surgical wound. Culture of the excised tissue and purulent discharge resulted in the isolation of a rare causative agent of fungal Fournier's gangrene,
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