Evidence map›Paper›PMID 41111646›Full record

ArticleCureus2025

A Rare Case of Necrotizing Soft Tissue Infection in the Labium Resulting From Candida glabrata.

Maria-Anthi Chantzi, Alexandra Marinou, Maria Papadoliopoulou, Theodoros Sidiropoulos, Nick Danias

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Maria-Anthi ChantziSchool of Medicine, National and Kapodistrian University of Athens, Athens, GRC.
Alexandra MarinouSchool of Medicine, National and Kapodistrian University of Athens, Athens, GRC.
Maria Papadoliopoulou4th Department of Surgery, Attikon University Hospital, National and Kapodistrian University of Athens, Athens, GRC.
Theodoros Sidiropoulos4th Department of Surgery, Attikon University Hospital, National and Kapodistrian University of Athens, Athens, GRC.
Nick Danias4th Department of Surgery, Attikon University Hospital, National and Kapodistrian University of Athens, Athens, GRC.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Necrotizing soft tissue infections (NSTIs) are severe infections affecting the skin, subcutaneous, and muscle tissue. Tissue destruction, systemic toxicity, and increased morbidity are usually observed. An aggressive form of NSTI is called Fournier's gangrene: it starts as a necrotizing fasciitis of the perineal and genital area and affects adjacent soft tissue. It exhibits an increased rate of morbidity, thus requiring a high index of clinical suspicion to secure early surgical debridement. A 58-year-old patient presented in the emergency department complaining of pain in the labia majora. Clinical examination revealed tenderness, erythema, edema, and the presence of a large condyloma on the left labium majus. The patient was admitted and was treated with an antibiotic, with no improvement. A crackling sensation of the affected labium was observed on subsequent examination. Imaging revealed signs of necrosis, and NSTI was confirmed. The patient underwent surgical debridement of the perineum along with removal of the condyloma. A vacuum-assisted closure device was used for secondary healing of the surgical wound. Culture of the excised tissue and purulent discharge resulted in the isolation of a rare causative agent of fungal Fournier's gangrene,

Indexed as

candida glabratafemalefournier gangrenefungal necrotising soft tissue infectionsnon-albicans candida

Identifiers

PMID41111646
PMCPMC12529435

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.