Evidence map›Paper›PMID 41111569›Full record

ArticleDiabetology international2025

Real-world use of finerenone in diabetic kidney disease: eGFR slope analysis with exploratory data on prior MRA use.

Yuka Yamao, Miwa Ota, Keizo Kanasaki

Abstract read
In one paragraph

Article in Diabetology international, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Observational
  2. Observational
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Yuka YamaoFaculty of Medicine, Internal Medicine I, Shimane University, 89-1 Enya-Cho, Izumo, Shimane 693-8501 Japan.
Miwa OtaFaculty of Medicine, Internal Medicine I, Shimane University, 89-1 Enya-Cho, Izumo, Shimane 693-8501 Japan.
Keizo KanasakiFaculty of Medicine, Internal Medicine I, Shimane University, 89-1 Enya-Cho, Izumo, Shimane 693-8501 Japan.ORCID 0000-0002-9563-502X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the post-SGLT2 inhibitor era, residual renal risk remains a major concern in diabetic kidney disease (DKD). Finerenone, a non-steroidal mineralocorticoid receptor antagonist (MRA), has shown cardiovascular and renal benefits in clinical trials. However, its effectiveness in patients previously treated with other MRAs remains unclear. We retrospectively analyzed 73 patients with DKD who were treated with finerenone at Shimane University Hospital between June 2022 and March 2024. The primary outcome was the change in estimated glomerular filtration rate (eGFR) slope before and after finerenone initiation. The mean eGFR slope significantly improved following finerenone initiation (-7.3 to -0.5 mL/min/1.73 m

Indexed as

Diabetic kidney diseaseeGFR slopeFinerenoneMineralocorticoid receptor antagonistReal-world evidenceSGLT2 inhibitor

Identifiers

PMID41111569
PMCPMC12532524

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.