Evidence map›Paper›PMID 41111120›Full record

SynthesisObesity surgery2025

Endoscopic Treatment of Staple-Line Leaks After Sleeve Gastrectomy in Patients with Obesity: Which One is the Best Option, if Any? A Systematic Review with Meta-Analysis and Meta-regression.

Giuseppe Galloro, Mariano Cesare Giglio, Alessia Chini, Rosa Maione, Matteo Pollastro, Rosa Vitale, Antonio Pisani, Mario Musella

Abstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Obesity surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Giuseppe GalloroDepartment of Clinical Medicine and Surgery, Digestive Surgical Endoscopy Unit, University of Naples Federico II, Naples, Italy. giuseppe.galloro@unina.it.
Mariano Cesare GiglioDepartment of Clinical Medicine and Surgery, Hepato-Pancreato-Biliary Surgery Unit, University of Naples Federico II, Naples, Italy.
Alessia ChiniDepartment of Clinical Medicine and Surgery, Digestive Surgical Endoscopy Unit, University of Naples Federico II, Naples, Italy.
Rosa MaioneDepartment of Clinical Medicine and Surgery, Digestive Surgical Endoscopy Unit, University of Naples Federico II, Naples, Italy. rosamaione95@libero.it.
Matteo PollastroDepartment of Clinical Medicine and Surgery, Digestive Surgical Endoscopy Unit, University of Naples Federico II, Naples, Italy.
Rosa VitaleDepartment of Clinical Medicine and Surgery, Digestive Surgical Endoscopy Unit, University of Naples Federico II, Naples, Italy.
Antonio PisaniGastroenterology II Unit, Gastroenterology Hospital ''Saverio de Bellis'', Castellana Grotte (Bari), Italy.
Mario MusellaDepartment of Clinical Medicine and Surgery, General Endocrine-Metabolic and Obesity Surgery Unit, University of Naples Federico II, Naples, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Laparoscopic sleeve gastrectomy (LSG) is the most common bariatric surgery, with staple-line leak (SLL) as its most severe complication. Various endoscopic treatments exist, but no universal algorithm is established. The aim of this paper is to estimate the success rates of different endoscopic techniques for SLL management. A search of Medline, Embase, and SCOPUS identified studies on endoscopic treatments. Pooled success rates were calculated using random-effects modeling. Seventy-nine studies (2205 patients) showed an overall success rate of 84.1%. Double-pigtail drainage (90.07%), endoscopic vacuum therapy (90.2%), and septotomy (88.25%) were most effective. Meta-regression indicated significantly higher success with double-pigtail drainage (p = 0.035). Endoscopic treatments, especially double-pigtail drainage and vacuum therapy, are highly effective for SLL. Further research is needed to compare techniques and evaluate additional clinical factors.

Indexed as

Anastomotic LeakGastrectomyLaparoscopyObesity, MorbidSurgical StaplingDrainageHumansTreatment OutcomeEndoscopic treatmentLaparoscopic sleeve gastrectomy (LSG)Meta-analysisMetabolic and bariatric endoscopyMeta-regressionObesityStaple-line leak (SLL)Systematic review

Identifiers

PMID41111120
PMCPMC12722327

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.