Evidence map›Paper›PMID 41110786›Full record

ArticleEnvironmental research2025

Associations of children's urinary metals with blood RNA N

Carolyn Gigot, Ya Li, Haotian Wu, Guadalupe Estrada-Gutierrez, Mari Cruz Tolentino, Alejandra Cantoral, Julio Landero, Martha M Téllez-Rojo, Robert O Wright, Yinsheng Wang and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Environmental research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Carolyn GigotColumbia University, Environmental Health Sciences, New York City, New York, United States of America. Electronic address: cg3525@cumc.columbia.edu.
Ya LiUniversity of California Riverside, Department of Chemistry, Riverside, CA, United States of America.
Haotian WuColumbia University, Environmental Health Sciences, New York City, New York, United States of America.
Guadalupe Estrada-GutierrezNational Institute of Perinatology, Mexico City, Mexico.
Mari Cruz TolentinoNational Institute of Perinatology, Mexico City, Mexico.
Alejandra CantoralIberoamerican University, Health Department, Mexico City, Mexico.
Julio LanderoIcahn School of Medicine at Mount Sinai, Environmental Medicine, New York City, New York, United States of America.
Martha M Téllez-RojoNational Institute of Public Health of Mexico (INSP), Center for Research in Nutrition and Health, Mexico City, Mexico.
Robert O WrightIcahn School of Medicine at Mount Sinai, Environmental Medicine, New York City, New York, United States of America.
Yinsheng WangUniversity of California Riverside, Department of Chemistry, Riverside, CA, United States of America.
Allison KupscoColumbia University, Environmental Health Sciences, New York City, New York, United States of America.

Funding

Stress, Lead, Iron Deficiency and NeurodevelopmentR01ES013744 · NIEHS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Robert O Wright · 2007 to 2026
$13.4M
Supplemental Training in Making Data FAIR and AI/ML ReadyT32ES007322 · NIEHS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Pam R Factor-Litvak, Allison Kupsco · 2000 to 2026
$12.1M
Chemical Biology of DNA and RNA AlkylationR35ES031707 · NIEHS · UNIVERSITY OF CALIFORNIA RIVERSIDE · PI Yinsheng Wang · 2020 to 2026
$6.1M
Metal Mixtures and NeurodevelopmentR01ES014930 · NIEHS · BRIGHAM AND WOMEN'S HOSPITAL · PI WRIGHT, ROBERT O · 2006 to 2010
$3.2M
Metal Mixtures, MicroRNAs and Metabolomics in Extracellular Vesicles, and Early-life Programming of Childhood Sleep Patterns: A Longitudinal StudyR01ES035478 · NIEHS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Dinesh Barupal, Allison Kupsco · 2024 to 2026
$2.1M
The Programming Research in Obesity, GRowth, Environment and Social Stress (PROGRESS) CohortR24ES028522 · NIEHS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Megan K Horton, Maria Jose Rosa · 2017 to 2026
$1.8M
The Programming Research in Obesity, GRowth, Environment and Social Stress (PROGRESS) CohortU24ES028522 · NIEHS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI HORTON, MEGAN K, ROSA, MARIA JOSE · 2024 to 2025
$719k
NIEHS NIH HHS R01 ES013744NIEHS NIH HHS R01 ES014930NIEHS NIH HHS R01 ES035478NIEHS NIH HHS R24 ES028522NIEHS NIH HHS R35 ES031707NIEHS NIH HHS T32 ES007322NIEHS NIH HHS U24 ES028522
6 · The paper itself

Abstract

backgroundPost-transcriptional RNA modifications (the epitranscriptome) regulate gene expression and represent a pathway through which environmental exposures can affect health. Two RNA modifications important for health and disease are N

methodsWe measured essential (cobalt, copper, selenium, zinc) and nonessential (arsenic, cadmium, chromium, cesium, mercury, antimony) metals in urine and total m

resultsMedian m

conclusionsExposure to nonessential metals may be related to global Am levels in children. Further research is warranted to evaluate potential roles of Am and m

Indexed as

AdenosineEnvironmental PollutantsChildCross-Sectional StudiesFemaleHumansMaleMetalsMexicoRNAAdenosineEnvironmental PollutantsMetalsN-methyladenosineRNA

Identifiers

PMID41110786
PMCPMC12676561

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.