Evidence map›Paper›PMID 41110317›Full record

Trial reportDiabetes & metabolic syndrome2025

A randomized pilot sleep and circadian behavior clinical trial to improve glycemic and psychological outcomes in young adults with type 1 diabetes (NCT04975230).

Bethany L Armentrout, Megan L Wenzell, Kingman P Strohl, Sybil L Crawford, Jamie R Wood, Chiang-Shan R Li, Ronald L Hickman, Stephanie Alisha Griggs

Abstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Diabetes & metabolic syndrome, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Bethany L ArmentroutCase Western Reserve University, Frances Payne Bolton School of Nursing, Cleveland, OH, 44106, USA. Electronic address: ba43@uw.edu.
Megan L WenzellCase Western Reserve University, Frances Payne Bolton School of Nursing, Cleveland, OH, 44106, USA. Electronic address: mla88@case.edu.
Kingman P StrohlPhysiology and Biophysics, Case Western Reserve University, School of Medicine, Cleveland, OH, 44106, USA. Electronic address: Kingman.strohl@uhhospitals.org.
Sybil L CrawfordUniversity of Massachusetts Chan Medical School, Tan Chingfen Graduate School of Nursing, Worcester, MA, 01655, USA. Electronic address: Sybil.crawford@umassmed.edu.
Jamie R WoodCase Western Reserve University, School of Medicine, Pediatric Endocrinology, University Hospitals Rainbow Babies and Children's Hospital, Cleveland, OH, 44106, USA. Electronic address: jamie.wood@uhhospitals.org.
Chiang-Shan R LiYale University, School of Medicine, New Haven, CT, 06519, USA. Electronic address: chiang-shan.li@yale.edu.
Ronald L HickmanCase Western Reserve University, Frances Payne Bolton School of Nursing, Cleveland, OH, 44106, USA. Electronic address: Ronald.hickman@case.edu.
Stephanie Alisha GriggsCase Western Reserve University, Frances Payne Bolton School of Nursing, Cleveland, OH, 44106, USA. Electronic address: stephanie.griggs2@emory.edu.

Funding

A Cognitive Behavioral Sleep Self-Management Intervention for Young Adults with Type 1 DiabetesR01DK136604 · NIDDK · CASE WESTERN RESERVE UNIVERSITY · PI GRIGGS, STEPHANIE ALISHA · 2023 to 2025
$2.1M
Sleep, Glycemia, and Self-Management in Young Adults with Type 1 Diabetes MellitusR00NR018886 · NINR · CASE WESTERN RESERVE UNIVERSITY · PI GRIGGS, STEPHANIE ALISHA · 2021 to 2023
$729k
NIDDK NIH HHS R01 DK136604NINR NIH HHS R00 NR018886
6 · The paper itself

Abstract

aimsTo investigate the preliminary efficacy of a cognitive behavioral sleep and circadian intervention on glycemic and psychological outcomes in young adults with type 1 diabetes.

methodsGlycemic and psychological outcomes were evaluated in 39 young adults (mean age 21.08, diabetes duration 11.7 years, mean glycated hemoglobin 8.46 %, 41 % female) from March 2022 to October 2023. Participants were randomly assigned (1:1) to a 12-week cognitive behavioral sleep and circadian condition (n = 21) or a time-balanced attention control condition (n = 18). Data were collected using continuous glucose monitors, research-grade actigraphy, and daily sleep surveys at baseline, post-intervention, and 3-month follow-up.

resultsThe cognitive behavioral sleep and circadian intervention condition showed significant improvements in glycemic outcomes, with reductions in the coefficient of variation and mean amplitude of glucose excursions three months post-intervention. It also resulted in decreased diabetes distress at both time points, unlike the Attention Control group, which had minimal changes.

conclusionsFuture research should confirm these preliminary findings in larger, more diverse samples with varied intervention lengths and a longer-term follow-up.

Indexed as

Circadian RhythmCognitive Behavioral TherapyDiabetes Mellitus, Type 1SleepAdolescentAdultBiomarkersBlood GlucoseFemaleFollow-Up StudiesGlycated HemoglobinGlycemic ControlHumansMalePilot ProjectsPrognosisBiomarkersBlood GlucoseGlycated Hemoglobinhemoglobin A1c protein, humanDiabetes mellitusSleep-promoting interventionType 1Young adult

Identifiers

PMID41110317
PMCPMC12595978

What OpenQuestion holds

Textmetadata
LicenceTDM
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.