Evidence map›Paper›PMID 41110031›Full record

ArticleSpine deformity2026

Artificial intelligence in early onset scoliosis: a scoping review.

Chuck Lam, Jennifer Tasong, Halil Bulut, Amy Udall, Tenghis Sukhbaatar, Gary Hoang, Aran Koye, JeeHwan Ahn, Fayez Ghazi, Duncan Loader and 4 more

Abstract readScoping Review
In one paragraph

Article in Spine deformity, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Chuck LamSchool of Medicine, University of Birmingham, Birmingham, UK. chuck.lam2@nhs.net.ORCID http://orcid.org/0009-0000-1970-3038
Jennifer TasongSchool of Medicine, University of Birmingham, Birmingham, UK.
Halil BulutCerrahpasa School of Medicine, Istanbul University Cerrahpasa, Istanbul, Turkey.
Amy UdallSchool of Medicine, University of Birmingham, Birmingham, UK.
Tenghis SukhbaatarSchool of Medicine, Imperial College London, London, UK.
Gary HoangSchool of Medicine, University of Birmingham, Birmingham, UK.
Aran KoyeSchool of Medicine, Imperial College London, London, UK.
JeeHwan AhnSchool of Medicine, Imperial College London, London, UK.
Fayez GhaziGeisel School of Medicine at Dartmouth, Hanover, USA.
Duncan LoaderBristol Royal Infirmary, Bristol, UK.
Conor T BoylanAintree University Hospital, Liverpool, UK.
Jwalant S MehtaSpine Surgery Unit, Royal Orthopaedic Hospital, Birmingham, UK.
George McKaySpine Surgery Unit, Royal Orthopaedic Hospital, Birmingham, UK.
Morgan JonesSpine Surgery Unit, Royal Orthopaedic Hospital, Birmingham, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeEarly onset scoliosis comprises spinal deformities in children younger than 10, creating challenges in diagnosis, risk assessment, and management. Timely intervention is vital, because untreated deformity can lead to cardiopulmonary compromise. Artificial intelligence and machine learning are reshaping orthopaedic care by improving detection, forecasting progression, and guiding treatment. This scoping review maps current use in this patient population.

methodsFollowing PRISMA ScR standards, we systematically searched PubMed, Embase, Web of Science, Cochrane, and Scopus for studies that developed, applied, or validated AI models to diagnose, manage, or predict outcomes in EOS.

resultsAfter removing duplicates, 352 records were screened, 22 full texts were reviewed, and 11 studies met inclusion criteria. Most investigations (63.6%) employed convolutional neural networks (CNNs) such as Mask R CNN, EfficientNet, and U Net. Ensemble learning with gradient boosting, random forest, and logistic regression (9.1%), Gaussian Naïve Bayes (9.1%), sparse additive machines (9.1%), and unsupervised clustering (9.1%) were also used. Image analysis dominated (72.7%), automating radiographic measurements (Cobb angle, skeletal maturity) and monitoring growing-rod distraction. Predictive models (27.3%) estimated prolonged hospital stay, unplanned reoperation, or postoperative complications. Mean accuracy was 91.2% (range 86.1% to 94.0%). Common limitations were small sample sizes, single-centre data, and limited external validation.

conclusionAI shows promise for EOS imaging and risk prediction, yet translation is hindered by methodological heterogeneity and scarce external validation. Future work should adopt standardised reporting, aggregate multicentre datasets, and test models prospectively in large cohorts.

Indexed as

Artificial IntelligenceScoliosisAge of OnsetChildHumansMachine LearningNeural Networks, ComputerArtificial intelligenceEarly onset scoliosisMachine learningScoping reviewSpine deformity

Identifiers

PMID41110031
PMCPMC12909398

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.