ReviewFASEB journal : official publication of the Federation of American Societies for Experimental Biology2025
Research Progress of RAD51AP1 in Malignant Tumors of the Female Reproductive System.
Review in FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Research Progress of RAD51AP1 in Malignant Tumors of the Female Reproductive System.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
Genomic instability may contribute to the occurrence and progression of malignant tumors of the female reproductive system. Homologous recombination repair (HRR) is vital in maintaining cellular genomic stability. RAD51-associated protein 1 (RAD51AP1) plays a vital role in HRR, mainly participating in the formation of displacement loop (D-loop), and is an important molecule for maintaining cellular genomic stability. Recent studies showed that RAD51AP1 was significantly overexpressed in a variety of cancer types and correlated with prognosis, suggesting that it may have a significant pro-carcinogenic effect. However, the mechanism underlying its pro-carcinogenic effect remains unclear, which may be closely associated with cancer stemness. Meanwhile, RAD51AP1 also plays an important role in resistance to radiotherapy and chemotherapy. Exploring RAD51AP1 and its regulatory molecules may provide new targets for overcoming cancer progression and treatment resistance. Here, we reviewed the latest research on RAD51AP1 in female reproductive system tumors and summarized its differential expression and prognostic implications. In this review, we also outlined the potential mechanisms of its procancer and drug resistance-promoting effects to provide several potential directions for further research.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.