Evidence map›Paper›PMID 41109745›Full record

ArticleJournal of primary care & community health

Digital Proton Pump Inhibitor Prescribing Education at The Point of Prescription: A Real-World Study in a Primary Care Setting.

Joshua Wray, Fergus deGrey-Warter, Erzsebet Horvath, Monika Haering, Patricia Aluko, Karel Kostev, Kate Plehhova

Abstract read
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Article in Journal of primary care & community health. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Joshua WrayReckitt Benckiser Healthcare Limited, Hull, United Kingdom.
Fergus deGrey-WarterReckitt Benckiser Healthcare Limited, Hull, United Kingdom.
Erzsebet HorvathReckitt Benckiser Healthcare Limited, Hull, United Kingdom.
Monika HaeringReckitt Benckiser, Heidelberg, Germany.
Patricia AlukoReckitt Benckiser Healthcare Limited, Hull, United Kingdom.ORCID 0000-0002-0743-9978
Karel KostevIQVIA, Epidemiology, Frankfurt am Main, Germany.ORCID 0000-0002-2124-7227
Kate PlehhovaReckitt Benckiser Healthcare Limited, Hull, United Kingdom.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundProton pump inhibitors (PPIs) are frequently prescribed in primary care, often for durations that exceed guideline recommendations. We evaluated whether a digital point‑of‑prescription educational intervention based on the updated March 2023 Deutsche Gesellschaft für Gastroenterologie, Verdauungs- und Stoffwechselkrankheiten (DGVS) GERD guideline could influence the prescribing patterns of primary care physicians (PCPs).

methodsWe conducted a 12‑month retrospective cohort study using anonymized prescription data from PCPs in Germany. Intervention physicians (n = 886) received EMR‑integrated pop‑up messages with guideline‑based recommendations and optional links to further content on the "Praxiswelt" (Practice World) educational platform. A matched control group (n = 886) received no messages. Physician engagement (click rates), PPI prescription volume, pack size, and use of ICD‑10 diagnosis codes were compared pre‑ (Q2-Q4 2022) and post‑guideline (Q2-Q4 2023). Analyses were descriptive.

resultsA total of 31 629 pop‑ups were displayed (mean 37.7 per physician); of these, 32.7% generated positive interactions, 0.4% negative, and 66.9% no interaction. PPI prescription volume changed by -2.8% in the intervention group versus +0.7% in controls. Most prescriptions exceeded the recommended 8‑week duration (91%-100%). ICD‑10 coding rates remained low (missing codes: intervention 75.2% pre-guideline vs 76.7% post-guideline; controls 90.0% vs 88.1%).

conclusionDigital pop‑up education at the point of prescription produced only minimal changes in prescribing volume and coding behavior. The limited effect may reflect alert fatigue, passive content, and single‑channel delivery. Future strategies should combine point‑of‑prescription alerts with interactive decision support, audit and feedback, and system‑level changes to improve both adherence and documentation.

Indexed as

Physicians, Primary CarePractice Patterns, Physicians'Primary Health CareProton Pump InhibitorsAdultDrug PrescriptionsFemaleGastroesophageal RefluxGermanyHumansMaleMiddle AgedPractice Guidelines as TopicRetrospective StudiesProton Pump InhibitorsEMR interventionGermanyprimary careproton pump inhibitorretrospective cohort study

Identifiers

PMID41109745
PMCPMC12547144

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.