Evidence map›Paper›PMID 41109665›Full record

ArticleThe American journal of pathology2026

Specialized Pro-Resolving Mediators MaR1 and LXA

Maureen E Haynes, Vivienne Fang, Meital Gewirtz, David P Sullivan, William A Muller

Abstract read
In one paragraph

Article in The American journal of pathology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Maureen E HaynesDepartment of Pathology, Northwestern University Feinberg School of Medicine, Chicago, Illinois.
Vivienne FangDepartment of Pathology, Northwestern University Feinberg School of Medicine, Chicago, Illinois.
Meital GewirtzDepartment of Pathology, Northwestern University Feinberg School of Medicine, Chicago, Illinois.
David P SullivanDepartment of Pathology, Northwestern University Feinberg School of Medicine, Chicago, Illinois.
William A MullerDepartment of Pathology, Northwestern University Feinberg School of Medicine, Chicago, Illinois. Electronic address: wamuller@northwestern.edu.

Funding

Transendothelial Migration of Leukocytes: Developing New Paradigms in Health and DiseaseR35HL155652 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI William A Muller · 2021 to 2026
$5.1M
Defining the temporospatial functions of neutrophils in acute airspace diseaseF31HL172345 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI HAYNES, MAUREEN · 2024 to 2024
$44k
NHLBI NIH HHS F31 HL172345NHLBI NIH HHS R35 HL155652
6 · The paper itself

Abstract

Gastric aspiration pneumonia involves chemical injury to the alveoli of the lungs with inflammation, tissue damage, and recruitment of polymorphonuclear leukocytes (PMNs). PMNs are also known to be involved in the production of specialized pro-resolving mediators (SPMs), small lipid molecules that contribute to the resolution of inflammation. This study aimed to identify target PMN-produced SPMs and interrogate their actions and potential use for therapeutic treatment after chemical injury. The data revealed that maresin 1 (MaR1), lipoxin A

Indexed as

Acute Lung InjuryDocosahexaenoic AcidsInflammationInflammation MediatorsLipoxinsNeutrophilsAnimalsEicosapentaenoic AcidMaleMiceMice, Inbred C57BLSpecialized Pro-Resolving Mediators5S,12R,18R-trihydroxy-6Z,8E,10E,14Z,16E-eicosapentaenoic acid7,14-dihydroxydocosa-4,8,10,12,16,19-hexaenoic acidDocosahexaenoic AcidsEicosapentaenoic AcidInflammation Mediatorslipoxin A4Lipoxins

Identifiers

PMID41109665
PMCPMC12881665

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.