Evidence map›Paper›PMID 41108744›Full record

ArticleACS synthetic biology2025

Cell-Free-Based Thermophilic Biocatalyst for the Synthesis of Amino Acids from One-Carbon Feedstocks.

Ray Westenberg, Shaafique Chowdhury, Ryan Cardiff, Kimberly Wennerholm, Alexander S Beliaev, James M Carothers, Pamela Peralta-Yahya

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS synthetic biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ray WestenbergBioengineering Program, Georgia Institute of Technology, Atlanta, Georgia 30332, United States.ORCID 0000-0001-7111-4484
Shaafique ChowdhurySchool of Chemical & Biomolecular Engineering, Georgia Institute of Technology, Atlanta, Georgia 30332, United States.
Ryan CardiffMolecular Engineering & Sciences Institute and Center for Synthetic Biology, University of Washington, Seattle, Washington 98195, United States.ORCID 0009-0001-0530-9010
Kimberly WennerholmSchool of Chemistry and Biochemistry, Georgia Institute of Technology, Atlanta, Georgia 30332, United States.
Alexander S BeliaevEnvironmental Molecular Sciences Division, Pacific Northwest National Laboratory, Richland, Washington 99354, United States.
James M CarothersMolecular Engineering & Sciences Institute and Center for Synthetic Biology, University of Washington, Seattle, Washington 98195, United States.
Pamela Peralta-YahyaBioengineering Program, Georgia Institute of Technology, Atlanta, Georgia 30332, United States.ORCID 0000-0002-0356-2274

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bioproduction from one-carbon compounds, such as formate, is an attractive prospect due to reduced energy requirements and the possibility for using CO

Indexed as

Amino AcidsCarbonAmmoniaBicarbonatesBiocatalysisCell-Free SystemEscherichia coliFormatesGlycineMetabolic EngineeringSerineAmino AcidsAmmoniaBicarbonatesCarbonFormatesformic acidGlycineSerinecarbon-negative synthesiscell-free expressionchemical bioproductionmetabolic engineeringthermophilic biocatalyst

Identifiers

PMID41108744
PMCPMC12645577

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.