Evidence map›Paper›PMID 41108653›Full record

ArticleMagnetic resonance in medicine2026

Multi-Frame Image Registration for Automated Ventricular Function Assessment in Single Breath-Hold Cine MRI Using Limited Labels.

Aya Ghoul, Paxstan Cassal Paulson, Andreas Lingg, Patrick Krumm, Kerstin Hammernik, Daniel Rueckert, Sergios Gatidis, Thomas Küstner

Abstract read
In one paragraph

Article in Magnetic resonance in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Aya GhoulMedical Image and Data Analysis (MIDAS.lab), Department of Interventional and Diagnostic Radiology, University Hospital of Tuebingen, Tuebingen, Germany.ORCID https://orcid.org/0009-0002-1221-1756
Paxstan Cassal PaulsonInstitute of Signal Processing and System Theory, University of Stuttgart, Stuttgart, Germany.
Andreas LinggMedical Image and Data Analysis (MIDAS.lab), Department of Interventional and Diagnostic Radiology, University Hospital of Tuebingen, Tuebingen, Germany.ORCID https://orcid.org/0000-0001-8583-8627
Patrick KrummMedical Image and Data Analysis (MIDAS.lab), Department of Interventional and Diagnostic Radiology, University Hospital of Tuebingen, Tuebingen, Germany.ORCID https://orcid.org/0000-0003-1705-8439
Kerstin HammernikSchool of Computation, Information and Technology, Technical University of Munich (TUM), Munich, Germany.ORCID https://orcid.org/0000-0002-2734-1409
Daniel RueckertSchool of Computation, Information and Technology, Technical University of Munich (TUM), Munich, Germany.ORCID https://orcid.org/0000-0002-5683-5889
Sergios GatidisMedical Image and Data Analysis (MIDAS.lab), Department of Interventional and Diagnostic Radiology, University Hospital of Tuebingen, Tuebingen, Germany.ORCID https://orcid.org/0000-0002-6928-4967
Thomas KüstnerMedical Image and Data Analysis (MIDAS.lab), Department of Interventional and Diagnostic Radiology, University Hospital of Tuebingen, Tuebingen, Germany.ORCID https://orcid.org/0000-0002-0353-4898

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis study aims to develop an automated framework for operator-independent assessment of cardiac ventricular function from highly accelerated images.

methodsWe introduce a deep learning framework that generates reliable ventricular volumetric parameters and strain measures from fully sampled and retrospectively accelerated MR images. This method integrates image registration, motion-compensated reconstruction, and segmentation in a synergetic loop for mutual refinement. The evaluation was performed on an in-house dataset of healthy and cardiovascular-diseased subjects. We examined the performance of the underlying tasks, including registration and segmentation, and their impact on derived parameters related to ventricular function.

resultsThe proposed approach demonstrates robustness to undersampling artifacts and requires limited annotation, while still reducing variability and errors for segmentation and registration. This translates to a

conclusionA comprehensive ventricular function analysis can be performed using highly accelerated cine MR data with minimal annotation effort. This multitasking strategy has the potential to enable more accessible cardiac function analysis within a single breath-hold.

Indexed as

Heart VentriclesImage Processing, Computer-AssistedMagnetic Resonance Imaging, CineVentricular FunctionAdultAlgorithmsArtifactsBreath HoldingDeep LearningFemaleHumansImage Interpretation, Computer-AssistedMaleReproducibility of ResultsRetrospective Studiescine MRIdeep learningimage registrationmotion‐compensated reconstructionsegmentationstrain

Identifiers

PMID41108653
PMCPMC12746400

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.