Evidence map›Paper›PMID 41108489›Full record

Observational studyHepatology international2026

Cirrhotic cardiomyopathy in children with biliary atresia and genetic intrahepatic cholestasis: clinical course and outcomes.

Tamoghna Biswas, Bikrant Bihari Lal, Rajeev Khanna, Vikrant Sood, Vikas Kohli, Neha Sharma, Jaswinder Singh Maras, Viniyendra Pamecha, Seema Alam

Abstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in Hepatology international, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Tamoghna BiswasDepartment of Pediatric Hepatology, Institute of Liver and Biliary Sciences, New Delhi, 110070, India.
Bikrant Bihari LalDepartment of Pediatric Hepatology, Institute of Liver and Biliary Sciences, New Delhi, 110070, India.
Rajeev KhannaDepartment of Pediatric Hepatology, Institute of Liver and Biliary Sciences, New Delhi, 110070, India.
Vikrant SoodDepartment of Pediatric Hepatology, Institute of Liver and Biliary Sciences, New Delhi, 110070, India.
Vikas KohliDepartment of Pediatric Cardiology, Delhi Child Heart Center, New Delhi, India.
Neha SharmaDepartment of Molecular and Cellular Medicine, Institute of Liver and Biliary Sciences, New Delhi, India.
Jaswinder Singh MarasDepartment of Molecular and Cellular Medicine, Institute of Liver and Biliary Sciences, New Delhi, India.
Viniyendra PamechaDepartment of Hepato-Pancreato-Biliary Surgery, Institute of Liver and Biliary Sciences, New Delhi, India.
Seema AlamDepartment of Pediatric Hepatology, Institute of Liver and Biliary Sciences, New Delhi, 110070, India. seema_alam@hotmail.com.ORCID http://orcid.org/0000-0003-0888-8625

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesCirrhotic cardiomyopathy (CCM) is an under recognized entity in children. The present study aimed to explore the prevalence and natural history of CCM and its impact on outcomes among children with biliary atresia (BA) and genetic intrahepatic cholestasis (GIC).

methodsThis was a prospective observational study. All children aged 0-18 years and diagnosed with either BA or GIC were included. Relevant clinical and biochemical parameters were recorded and transthoracic echocardiography was done. Left ventricular mass index (LVMI) ≥ 95 g/m

resultsEighty nine children were included in the study, 64 with BA and 25 with GIC. Prevalence of CCM in children with BA and GIC were 53.13% and 48% respectively. LVMI (g/m

conclusionsCCM is prevalent in almost half of patients with BA and GIC and is associated with decreased NLS and OS. Serum bile acids were significantly higher in children with CCM.

Indexed as

Biliary AtresiaCardiomyopathiesCholestasis, IntrahepaticLiver CirrhosisAdolescentChildChild, PreschoolEchocardiographyFemaleHumansInfantInfant, NewbornLiver TransplantationMalePrevalenceProspective StudiesBiliary atresiaCirrhotic cardiomyopathyLiver transplantationProgressive familial intrahepatic cholestasis

Identifiers

PMID41108489

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.