ArticleNeurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology2025
Is gaitrite system sensitive in discriminating gait pattern of subjects affected by Charcot Marie tooth? A pilot study.
Article in Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Commentary on "Is gaitrite system sensitive in discriminating gait pattern of subjects affected by Charcot Marie tooth? A pilot study".Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026Article
Corrections and comments
- Commented on by
Authors and funding
14 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCharcot-Marie-Tooth (CMT) disease is the most common hereditary neuropathy, characterized by progressive distal muscle weakness and gait abnormalities, impacting patients mobility and quality of life. Despite efforts to develop effective treatments, pharmacological options remain limited. Evaluation of gait function is crucial for assessing disease progression and treatment efficacy.
aimThis study compared the sensitivity of clinical and instrumental outcome measures (OM) in discriminating CMT patients and identifying key spatio-temporal gait parameters and their correlations with clinical measures.
methodsEighteen CMT patients and 18 healthy age-matched subjects (HS) were evaluated using clinical scales and instrumental gait analysis. Clinical measures included the 10 m walk test (10MWT), 6-minutes walk test (6MWT), Berg balance scale (BBS), Short Physical Performance Battery (SPPB), CMT Examination Score (CMTES), and Walk12 scale. Instrumental evaluation utilized the GAITRite electronic walkway system to assess spatio-temporal parameters. Correlations between clinical and instrumental parameters were examined.
resultsCMT patients exhibited significantly lower performance in clinical scales compared to HS. Instrumental evaluation revealed significant differences in stride length, velocity, stance percentage, and swing percentage between CMT patients and HS. Correlation analysis demonstrated associations between clinical and instrumental measures, particularly with stride length, gait speed, and balance assessments.
conclusionThe GAITRite system demonstrated sensitivity in discriminating CMT patients and controls, highlighting gait abnormalities consistent with previous literature findings. Correlations between instrumental and clinical measures suggest potential for objective gait assessment in CMT management. Further research with larger cohorts is warranted to validate these findings and assess longitudinal gait changes in CMT.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.