Evidence map›Paper›PMID 41108449›Full record

ReviewCurrent nutrition reports2025

Vitamin C in Pregnancy: A Key Modulator of Fetal Growth and Epigenetic Stability.

Burcu Ersoy-Demiryurek, Makbule Gezmen-Karadag

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current nutrition reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Burcu Ersoy-DemiryurekFaculty of Health Sciences, Department of Nutrition and Dietetics, Gazi University, Biskek Main St. 6. St No: 2, Emek, Cankaya, Ankara, 06490, Turkey. burcuersoy@gazi.edu.tr.ORCID http://orcid.org/0000-0001-9883-8095
Makbule Gezmen-KaradagFaculty of Health Sciences, Department of Nutrition and Dietetics, Gazi University, Biskek Main St. 6. St No: 2, Emek, Cankaya, Ankara, 06490, Turkey.ORCID http://orcid.org/0000-0003-3202-3250

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewAdequate vitamin C intake during pregnancy is crucial to support adequate growth and development of the fetus. Vitamin C, besides its involvement in numerous biological functions, is notable for its regulatory impact on gene expression. RECENT

findingsResearch shows that not getting enough vitamin C during pregnancy may be linked to adverse effects, such as shorter telomeres, problems with DNA methylation, higher rates of cell death in the placenta, and lower birth weight. Moreover, vitamin C offers genetic safeguarding against detrimental environmental influences and facilitates the maturation of the fetal immune system. Its involvement in epigenetic regulation contributes to managing processes, including germ cell development, neurodevelopment, and fertility. We emphasize that long-term health effects require sufficient vitamin C consumption during pregnancy. This review assesses the influence of maternal vitamin C intake on fetal growth and development based on existing literature.

Indexed as

Ascorbic AcidEpigenesis, GeneticFetal DevelopmentMaternal Nutritional Physiological PhenomenaDNA MethylationFemaleHumansPregnancyAscorbic AcidDNA methylationEpigeneticsFetal developmentPregnancyVitamin c

Identifiers

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.