Evidence map›Paper›PMID 41108386›Full record

ArticleGraefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie2026

Retinal morphological changes detected by wide-field optical coherence tomography in eyes after vitrectomy for proliferative diabetic retinopathy.

Yosuke Fukuda, Keijiro Ishikawa, Kodai Yuge, Kohei Kiyohara, Yusuke Maehara, Yuta Yasaka, Wei Tan, Rui Ji, Kenichiro Mori, Takahito Nakama and 5 more

Abstract read
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In one paragraph

Article in Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Yosuke FukudaDepartment of Ophthalmology, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-Ku, Fukuoka, 812-8582, Japan.ORCID http://orcid.org/0000-0002-0201-8541
Keijiro IshikawaDepartment of Ophthalmology, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-Ku, Fukuoka, 812-8582, Japan. ishikawa.keijiro.609@m.kyushu-u.ac.jp.
Kodai YugeDepartment of Ophthalmology, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-Ku, Fukuoka, 812-8582, Japan.
Kohei KiyoharaDepartment of Ophthalmology, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-Ku, Fukuoka, 812-8582, Japan.
Yusuke MaeharaDepartment of Ophthalmology, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-Ku, Fukuoka, 812-8582, Japan.
Yuta YasakaDepartment of Ophthalmology, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-Ku, Fukuoka, 812-8582, Japan.
Wei TanDepartment of Ophthalmology, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-Ku, Fukuoka, 812-8582, Japan.
Rui JiDepartment of Ophthalmology, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-Ku, Fukuoka, 812-8582, Japan.
Kenichiro MoriDepartment of Ophthalmology, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-Ku, Fukuoka, 812-8582, Japan.
Takahito NakamaDepartment of Ophthalmology, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-Ku, Fukuoka, 812-8582, Japan.
Shoji NotomiDepartment of Ophthalmology, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-Ku, Fukuoka, 812-8582, Japan.
Satomi ShioseDepartment of Ophthalmology, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-Ku, Fukuoka, 812-8582, Japan.
Atsunobu TakedaDepartment of Ophthalmology, Oita University of Faculty of Medicine, Oita, Japan.
Yusuke MurakamiDepartment of Ophthalmology, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-Ku, Fukuoka, 812-8582, Japan.
Koh-Hei SonodaDepartment of Ophthalmology, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-Ku, Fukuoka, 812-8582, Japan.

Funding

Grant-in-Aid for Transformative Research Areas 25H01289Grants-in-Aid for Scientific Research from KAKENHI #JP23K09046Grants-in-Aid for Scientific Research from KAKENHI #JP24KJ1780the Bayer Retina Award Foundation the Bayer Retina Award Foundationthe Eye Research Foundation for the Aged the Eye Research Foundation for the Agedthe ROHTO Award the ROHTO Awardthe Takeda Science Foundation the Takeda Science Foundation
6 · The paper itself

Abstract

purposeProliferative diabetic retinopathy (PDR) is a severe vitreoretinal disease that can lead to significant visual impairment. Vitrectomy is commonly performed in advanced cases; however, postoperative complications, such as proliferative membrane formation and retinal detachment may still occur. Early detection of these complications is essential for timely intervention and prevention of further vision loss. Retinal morphological changes, including tractional retinal detachment due to re-proliferation, may develop after vitreoretinal surgery. This study aimed to evaluate postoperative retinal morphological changes in PDR using wide-field optical coherence tomography (WF-OCT).

methodsSeventy-five eyes from 64 patients with PDR who underwent vitrectomy and had high-quality WF-OCT images taken at 1 and 2 months postoperatively were included. Subtracted wide-field retinal thickness map images were generated to analyze changes in retinal thickness.

resultsRetinal thickness changes were detected in 171 subfields across 64 eyes. The most common cause was the resolution of traction (51.5%), followed by traction worsening due to postoperative proliferative membrane formation (17.0%). Resolution of retinal edema was observed in 16 central and five peripheral subfields, whereas worsening was noted in five central and one peripheral subfield. Retinal thickness changes due to worsening traction were identified in four central and 25 peripheral subfields.

conclusionWF-OCT effectively detected postoperative retinal morphological changes in eyes with PDR, including changes in the peripheral retina. These findings highlight the clinical utility of WF-OCT for postoperative monitoring and treatment planning.

Indexed as

Diabetic RetinopathyPostoperative ComplicationsRetinaTomography, Optical CoherenceVisual AcuityVitrectomyAdultAgedFemaleFollow-Up StudiesHumansMaleMiddle AgedPostoperative PeriodRetrospective StudiesProliferative diabetic retinopathyProliferative membraneRetinal detachmentRetinal thicknessWide-field optical coherence tomography

Identifiers

PMID41108386

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.