Evidence map›Paper›PMID 41108316›Full record

ArticleJACC. Case reports2025

Sinus of Valsalva Aneurysm Rupture Causing Ventricular Septal Dissection With Left Ventricular Penetration.

Lei Liu, Xiuling Ma, Hui Chen, Yanfei Mo, Ning Zhang, Jing Yao, Xuelin Yang, Aijuan Fang

Abstract readCase Reports
In one paragraph

Article in JACC. Case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Lei LiuDepartment of Ultrasound Medicine, Nanjing University Medical School Affiliated Nanjing Drum Tower Hospital, Nanjing, China.
Xiuling MaDepartment of Ultrasound Medicine, Nanjing University Medical School Affiliated Nanjing Drum Tower Hospital, Nanjing, China.
Hui ChenDepartment of Ultrasound Medicine, Nanjing University Medical School Affiliated Nanjing Drum Tower Hospital, Nanjing, China.
Yanfei MoDepartment of Cardiology, China Pharmaceutical University Affiliated Pukou Hospital of Chinese Medicine, Nanjing, China.
Ning ZhangDepartment of Ultrasound Medicine, Nanjing University Medical School Affiliated Nanjing Drum Tower Hospital, Nanjing, China.
Jing YaoDepartment of Ultrasound Medicine, Nanjing University Medical School Affiliated Nanjing Drum Tower Hospital, Nanjing, China.
Xuelin YangDepartment of Anesthesiology, Nanjing University Medical School Affiliated Nanjing Drum Tower Hospital, Nanjing, China.
Aijuan FangDepartment of Ultrasound Medicine, Nanjing University Medical School Affiliated Nanjing Drum Tower Hospital, Nanjing, China. Electronic address: fajglyy0607@126.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRupture of a sinus of Valsalva aneurysm is most often congenital, resulting from inherent weakness at the aortic-annular junction. Rupture into the interventricular septum is a rare complication. CASE SUMMARY: A 58-year-old man presented with recurrent chest tightness consistent with NYHA functional class III symptoms and hypotension (blood pressure: 103/43 mm Hg). Transthoracic echocardiography, transesophageal echocardiography, and computed tomography angiography demonstrated rupture of a right coronary sinus aneurysm into the interventricular septum, forming a dissection that communicated with the left ventricle via 2 defects. Emergent surgical repair led to complete resolution of the dissection. DISCUSSION: This case illustrates the diagnostic challenges associated with rupture of a sinus of Valsalva aneurysm complicated by ventricular septal dissection. It emphasizes the critical role of multimodal imaging in detecting left ventricular involvement, and it underscores the necessity of prompt surgical intervention to reduce mortality. TAKE-HOME MESSAGE: Early identification using multimodal imaging and immediate surgical repair are essential for favorable outcomes in rare cases of sinus of Valsalva aneurysm rupture complicated by ventricular septal dissection and left ventricular penetration.

Indexed as

multimodal imagingsinus of Valsalva aneurysm rupturesurgical repairventricular septal dissection

Identifiers

PMID41108316
PMCPMC12790223

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.