Evidence map›Paper›PMID 41108202›Full record

ArticleThe Journal of comparative neurology2025

Organization of the Auditory Brainstem in a Lizard, Gekko gecko. II. Afferent and Efferent Projections of Nuclei of the Lateral Lemniscus and the Torus Semicircularis.

Dawei Han, Yezhong Tang, Jakob Christensen-Dalsgaard, Wenru Liang, Catherine E Carr

Abstract read
In one paragraph

Article in The Journal of comparative neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Dawei HanDepartment of Biology, University of Maryland, College Park, Maryland, USA.
Yezhong TangDepartment of Biology, University of Maryland, College Park, Maryland, USA.
Jakob Christensen-DalsgaardInstitute of Biology, University of Southern Denmark, Odense, Denmark.
Wenru LiangDepartment of Biology, University of Maryland, College Park, Maryland, USA.
Catherine E CarrDepartment of Biology, University of Maryland, College Park, Maryland, USA.

Funding

CELLULAR MECHANISMS UNDERLYING SOUND LOCALIZATIONR01DC000436 · NIDCD · UNIV OF MARYLAND, COLLEGE PARK · PI CARR, CATHERINE EMILY · 1994 to 2017
$6.1M
Development of Temporal Fine structureR01DC019341 · NIDCD · UNIV OF MARYLAND, COLLEGE PARK · PI CARR, CATHERINE EMILY · 2021 to 2025
$1.6M
THE ROLE OF INHIBITION IN THE AUDITORY BRAINSTEMF32DC000466 · NIDCD · UNIVERSITY OF WASHINGTON · PI BURGER, R. MICHAEL · 2001 to 2003
$118k
Carlsbergfondet 2009-01-0684Danmarks Grundforskningsfond 09-065990National Natural Science Foundation of ChinaNIDCD NIH HHS F32 DC000466NIDCD NIH HHS R01 DC000436NIDCD NIH HHS R01 DC019341NIH HHS DC00436NIH HHS DC019341NIH HHS P30 DC0466NSFC 31272304Velux Fonden
6 · The paper itself

Abstract

In reptiles, two taxa, lepidosaurs and archosaurs, have ears with thin tympanic membranes that permit sensitive hearing of high-frequency sounds in air. The organization of their central auditory systems may reflect this increased sensitivity to sound. To understand auditory processing in lepidosaurs further, we used tract tracing techniques to examine the organization and connections of the lemniscal and midbrain auditory nuclei in the Tokay gecko. The nuclei of the lateral lemniscus (LLD) consist of anterior (LLDa), medial (LLDm), and posterior (LLDp) subdivisions and receive ascending projections from the contralateral cochlear nuclei (nucleus angularis and nucleus laminaris) and the ipsilateral dorsal superior olive (SOd). LLD projects to the ventral division of the ipsilateral torus semicircularis (TS). In the Tokay gecko, the central nucleus of the torus (TSC) is large, with two major subdivisions, ventral and dorsal. Caudally, the TSC is fused at the midline, with the dorsal divisions adjoining their contralateral homolog. More rostrally, the TSC bifurcates to form two wings below the tectal ventricles. The ventral division of the TSC receives ascending input from NA/NL, SOd, and the lateral lemniscal complex, while both the dorsal and ventral divisions send descending projections to the lateral lemniscal complex. The TSC projects to the auditory thalamic nucleus medialis through the tractus opticus lateralis. Physiological recordings from TSCv injection sites revealed a patchy distribution of best frequencies, while recordings in TSCd were characterized by broad frequency tuning. The tract tracing results revealed conserved anatomical patterns of ascending auditory connections in lizards and archosaurs.

Indexed as

Auditory PathwaysBrain StemLizardsSemicircular CanalsAfferent PathwaysAnimalsEfferent PathwaysFemaleMalelateral lemniscuslizardNeurobiotin (RRID:AB_2336606)Neurolucida (RRID:SCR_001775)superior olivetonotopytorus semicircularistract tracing

Identifiers

PMID41108202
PMCPMC12534725

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.