Evidence map›Paper›PMID 41108106›Full record

ReviewThe Biochemical journal2025

Vesicular transport in the autophagic route: RAB GTPases as pivotal regulators of autophagy.

Romina Abba, María Isabel Colombo

Abstract readReview
In one paragraph

Review in The Biochemical journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Autophagy in Ovarian Cancer, an Opportunity or an Additional Threat?International journal of molecular sciences · 2026
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Romina AbbaFacultad de Ciencias Médicas, Laboratorio de Mecanismos Moleculares Implicados en el Tráfico Vesicular y la Autofagia-Instituto de Histología y Embriología (IHEM)- Universidad Nacional de Cuyo, CONICET.ORCID 0000-0002-5239-2400)
María Isabel ColomboFacultad de Ciencias Médicas, Laboratorio de Mecanismos Moleculares Implicados en el Tráfico Vesicular y la Autofagia-Instituto de Histología y Embriología (IHEM)- Universidad Nacional de Cuyo, CONICET.ORCID 0000-0002-5788-9256

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Autophagy is recognized as one of the two main intracellular recycling pathways that play an essential role in cellular homeostasis by maintaining accurate energy levels and carrying out quality control functions. One of the major autophagic mechanisms, the so-called macroautophagy, is involved in the lysosomal degradation of different cytoplasmic components, such as long-lived proteins and damaged or dysfunctional organelles. Numerous studies have demonstrated that participation of intracellular membrane trafficking events is key for the progression of autophagy. In this review, we will focus on the small GTPases of the RAS-related in brain protein family, which have a crucial role in vesicular transport.

Indexed as

Autophagyrab GTP-Binding ProteinsTransport VesiclesAnimalsBiological TransportHumansLysosomesProtein Transportrab GTP-Binding Proteinsautophagymembrane trafficRAB GTPases

Identifiers

PMID41108106
PMCPMC12687433

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.