Evidence map›Paper›PMID 41107948›Full record

ArticleJournal of cardiothoracic surgery2025

Clinical insights and management outcomes of tracheoesophageal and bronchoesophageal fistulas: a 20-year case series review.

Salem Algomaa Alhadid, Sakhr Alshwayyat, Hamdah Hanifa, Noor Almasri, Zaid Taimeh, Mustafa Alshwayyat, Tala Abdulsalam Alshwayyat, Alhareth M Amro, Bassam Darwish

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Article in Journal of cardiothoracic surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in
1citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

9 authors.

Salem Algomaa AlhadidDepartment of Thoracic Surgery, Al Mouwasat University Hospital, Damascus University, Damascus, Syria.
Sakhr AlshwayyatKern Medical (UCLA David Geffen School of Medicine affiliate), Bakersfield, CA, USA.
Hamdah HanifaFaculty of Medicine, University of Kalamoon, Al-Nabk, Syria. hamdahhanifa@gmail.com.ORCID http://orcid.org/0000-0003-2970-7379
Noor AlmasriUniversity of Jordan, Amman, Jordan.
Zaid TaimehJordanian Royal Medical Services, Amman, Jordan.
Mustafa AlshwayyatFaculty of Medicine, Jordan University of Science and Technology, Irbid, Jordan.
Tala Abdulsalam AlshwayyatPrincess Basma Teaching Hospital, Irbid, Jordan.
Alhareth M AmroFaculty of Medicine, Al-Quds University, Jerusalem, Palestine.
Bassam DarwishDepartment of Thoracic Surgery, Al Mouwasat University Hospital, Damascus University, Damascus, Syria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAbnormal connections between the trachea and esophagus, known as tracheoesophageal fistula (TEFs) and bronchoesophageal fistula (BEFs), are uncommon but potentially life-threatening conditions that can result in severe complications. This study aimed to explore the anatomical features, underlying causes of TEF and BEF and evaluate the treatment efficacy.

methodsThis retrospective study reviewed 15 cases of TEF/BEF treated at the University Hospital from 2001 to 2020. It examines the anatomical features, underlying causes, and treatment outcomes of these fistulas and evaluates various treatment modalities, such as open surgery, tracheal and esophageal stenting, and gastrostomy/jejunostomy.

resultsThis study included 15 patients (aged 15–65 years). Most cases were non-malignant (80%), mainly due to post-intubation injuries, while 20% were associated with malignancies, such as lymphoma and esophageal cancer. The fistulas were mostly located in the mid-trachea, with 40% measuring 1–3 cm. Gastrostomy/jejunostomy is the most common treatment option, particularly in malignant cases. The morbidity rate was 46.7%, with tracheal stenosis being the most frequent complication and no deaths reported. Follow-up (1–23 months) showed significant improvement in benign TEFs but no improvement in malignant TEFs.

conclusionThis study highlights the challenges in managing TEF/BEF and advocates treatment plans tailored to the specific etiology and characteristics of the fistula. These findings contribute to the limited existing literature on acquired TEF/BEF, suggesting that a multidisciplinary approach is essential for optimizing patient outcomes in these complex cases.

Indexed as

Bronchial FistulaEsophageal FistulaTracheoesophageal FistulaAdolescentAdultAgedFemaleHumansMaleMiddle AgedRetrospective StudiesTreatment OutcomeYoung AdultBronchoesophageal fistulaEsophageal neoplasmsMorbidityTracheoesophageal fistulaTreatment outcome

Identifiers

PMID41107948
PMCPMC12535024

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.