Evidence map›Paper›PMID 41107928›Full record

ArticleBMC medical ethics2025

Evaluating trustworthiness in AI-Based diabetic retinopathy screening: addressing transparency, consent, and privacy challenges.

Anshul Chauhan, Debarati Sarkar, Garima Singh Verma, Harsh Rastogi, Karthik Adapa, Mona Duggal

Abstract read
In one paragraph

Article in BMC medical ethics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Anshul Chauhan *Postgraduate Institute of Medical Research and Education, Chandigarh, India.
Debarati Sarkar *Interdisciplinary Research Programme, Indian Institute of Technology, Jodhpur, India.
Garima Singh VermaPostgraduate Institute of Medical Research and Education, Chandigarh, India.
Harsh RastogiPostgraduate Institute of Medical Research and Education, Chandigarh, India.
Karthik AdapaDepartment of Radiation Oncology, UNC School of Medicine, Chapel Hill, USA.
Mona DuggalIndian Council of Medical Research (ICMR) - National Institute of Research in Digital Health and Data Science (NIRDHDS), Ansari Nagar East, 110029, New Delhi, India. monaduggal2@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundArtificial intelligence (AI) offers significant potential to drive advancements in healthcare; however, the development and implementation of AI models present complex ethical, legal, social, and technical challenges, as data practices often undermine regulatory frameworks in various regions worldwide. This study explores stakeholder perspectives on the development and deployment of AI algorithms for diabetic retinopathy (DR) screening, with a focus on ethical risks, data practices, governance, and emerging shortcomings in the Global South AI discourse.

methodsFifteen semi-structured interviews were conducted with ophthalmologists, program officers, AI developers, bioethics experts, and legal professionals. Thematic analysis was guided by OECD principles for responsible AI stewardship. Interviews were analyzed using MAXQDA software to identify themes related to AI trustworthiness and ethical governance.

resultsSix key themes emerged regarding the perceived trustworthiness of AI: algorithmic effectiveness, responsible data collection, ethical approval processes, explainability, implementation challenges, and accountability. Participants reported critical shortcomings in AI companies' data collection practices, including a lack of transparency, inadequate consent processes, and limited patient awareness about data ownership. These findings highlight how unchecked data collection and curation practices may reinforce data colonialism in low and middle-income healthcare systems.

conclusionEnsuring trustworthy AI requires transparent and accountable data practices, robust patient consent mechanisms, and regulatory frameworks aligned with ethical and privacy standards. Addressing these issues is vital to safeguarding patient rights, preventing data misuse, and fostering responsible AI ecosystems in the Global South.

Indexed as

Artificial IntelligenceConfidentialityDiabetic RetinopathyInformed ConsentMass ScreeningPrivacyTrustAlgorithmsHumansQualitative ResearchStakeholder ParticipationArtificial intelligenceDiabetic retinopathy screeningTrustworthiness

Identifiers

PMID41107928
PMCPMC12532412

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.