Evidence map›Paper›PMID 41107917›Full record

ArticleEuropean journal of medical research2025

Burden of environmental heat and cold exposure and its attributable risk factors in 204 countries and territories (1990-2021).

Zhongyong Xie, Zhihua Huang, Wenmin Luo, Wei Du

Abstract read
In one paragraph

Article in European journal of medical research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Zhongyong XieJinan University, Guangzhou, Guangdong, China. xzhongy804@163.com.
Zhihua HuangDepartment of Pediatrics, Huizhou First Maternal and Child Health Care Hospital, Huizhou, Guangdong, China.
Wenmin LuoDepartment of Pediatrics, Huizhou First Maternal and Child Health Care Hospital, Huizhou, Guangdong, China.
Wei DuDepartment of Pediatrics, Huizhou First Maternal and Child Health Care Hospital, Huizhou, Guangdong, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEnvironmental heat and cold exposure poses significant public health challenges worldwide. Understanding the global, regional, and national burden of disease, as well as sociodemographic and risk factor associations, is essential for targeted interventions.

methodsThis secondary data analysis utilized age-standardized incidence rates (ASIR), mortality rates (ASMR), and Disability-Adjusted Life Years (DALYs) rates from the Global Burden of Disease Study 2021 to assess the health impacts of environmental heat and cold exposure globally from 1990 to 2021. Regional and national variations, as well as age, sex, and Socio-demographic Index (SDI) patterns, were analyzed. Health workforce density data from WHO were incorporated to examine associations with temperature-attributable burden.

resultsIn 2021, 3.4 million incident cases (ASIR: 45.1 per 100,000; 95% UI: 42.3-48.1) and 36,000 deaths (ASMR: 0.4 per 100,000; 95% UI: 0.3-0.5) were attributed to environmental heat and cold exposure worldwide, with 1.68 million DALYs (age-standardized rate: 20.4 per 100,000; 95% UI: 18.9-22.1). From 1990 to 2021, DALYs decreased by 53% (95% UI: 49-57%), highlighting global progress. However, disparities persist, with Central Asia and sub-Saharan Africa exhibiting the highest burden. Mongolia reported the highest national rates (ASIR: 366.4; ASMR: 5.2; DALY rate: 238.1 per 100,000). Men generally faced greater risks than women, particularly in older age groups. Cold exposure contributed 68% of total temperature-related DALYs, with opposing SDI gradients for heat (negative correlation) and cold (positive correlation) burden.

conclusionsWhile global reductions in temperature-attributable burden demonstrate progress, significant regional and national disparities persist, particularly in low-SDI regions. Effective healthcare policies, health workforce strengthening, and targeted interventions are critical to reducing the persistent burden in vulnerable areas.

Indexed as

Cold TemperatureEnvironmental ExposureHot TemperatureAdolescentAdultAgedChildDisability-Adjusted Life YearsFemaleGlobal Burden of DiseaseGlobal HealthHumansIncidenceInfantMaleMiddle AgedDisability-adjusted life years [MeSH]Extreme temperature [MeSH]Global burden of disease [MeSH]Mortality [MeSH]Risk factors [MeSH]Socioeconomic factors [MeSH]

Identifiers

PMID41107917
PMCPMC12534928

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.