ArticleBMC infectious diseases2025
Chest CT findings in drug-resistant pulmonary tuberculosis: a comparative analysis of elderly and non-elderly patients.
Article in BMC infectious diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Tuberculosis in Pregnancy: An Updated Narrative Review.Diagnostics (Basel, Switzerland) · 2026Review
- Application of Clinical-Radiomics Fusion Model in Predicting Drug Resistance of Cavitary Pulmonary Tuberculosis.Infection and drug resistance · 2026Article
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Authors and funding
4 authors.
Funding
Abstract
backgroundDrug-resistant pulmonary tuberculosis (DR-TB) remains a critical public health challenge, particularly affecting vulnerable populations such as the elderly, who exhibit higher morbidity and mortality rates. This study aims to elucidate the chest CT characteristics of DR-TB in elderly patients to improve diagnostic accuracy and guide individualized treatment strategies.
methodsA retrospective analysis of 183 confirmed DR-TB cases (Huai'an Infectious Disease Hospital, June 2013-June 2023) compared chest CT findings (lesion distribution, extent, and morphology) between elderly patients (≥ 60 years) and non-elderly patients (14-59 years).
resultsKey findings reveal that elderly patients demonstrate a higher frequency of extensive lung involvement, with 76% exhibiting lesions in all lung lobes compared to 40.74% in the non-elderly group (P < 0.001). Additionally, the elderly group displayed significantly more pathological features, such as segmental and lobar shadows (61.33% vs. 45.37%, P = 0.033) and lung destruction (22.67% vs. 11.11%, P = 0.035).
conclusionThe identification of risk factors on chest CT, including the presence of pulmonary and bronchial lesions, highlights the necessity for tailored screening and management strategies for elderly DR-TB patients.
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