ArticleBMC ophthalmology2025
Three-dimensional choroidal parameter differences in myopic anisometropia.
Article in BMC ophthalmology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Quantitative color fundus photography parameters as potential biomarkers of axial length progression: evidence from a machine learning cohort study.Frontiers in cell and developmental biology · 2026Article
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5 authors.
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Abstract
backgroundTo quantitatively compare 3D choroidal parameters between fellow eyes in individuals with varying degrees of myopic anisometropia and evaluate their correlations with interocular differences in spherical equivalent (△SE) and axial length (△AL).
methodsThis retrospective cross-sectional study enrolled 102 participants (204 eyes) categorized into low (△SE < 2.0D), moderate (2.0D ≤ △SE < 3.0D), and high (△SE ≥ 3.0D) anisometropia groups. Choroidal parameters, including choroidal vascular volume (CVV), choroidal stroma volume (CSV), and 3D choroidal vascularity index (3D-CVI), were measured using swept-source optical coherence tomography (SS-OCT). Retinal vessel density (VD) and regional variations were analyzed.
resultsCVV and CSV were significantly lower in more myopic eyes across all groups (P < 0.05), with the greatest reductions observed in the high anisometropia group. Nasal regions exhibited the strongest correlations between △CVV/△CSV and △SE/△AL (coefficients up to 0.403, P < 0.001). No interocular differences in 3D-CVI were detected (P > 0.05). Retinal VD in the high anisometropia group was elevated in more myopic eyes (P < 0.05), suggesting compensatory microvascular changes.
conclusionThree-dimensional choroidal metrics, particularly CVV and CSV, reflect myopic severity in anisometropia, with nasal choroid demonstrating heightened vulnerability to axial elongation. These findings highlight the potential of volumetric choroidal imaging for evaluating myopic structural changes and underscore the need for further longitudinal studies to elucidate causal mechanisms.
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