Evidence map›Paper›PMID 41107640›Full record

Trial reportAmino acids2025

Evaluation of processing of canola protein isolate on postprandial plasma amino acid profiles in healthy, young females.

Noortje Boot, Wesley J H Hermans, Ines Warnke, Alex Overman, Janneau M X van Kranenburg, Joan M Senden, Lex B Verdijk, Luc J C van Loon

Abstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Amino acids, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Noortje BootDepartment of Human Biology, NUTRIM Institute of Nutrition and Translational Research in Metabolism, Department of Human Biology, Maastricht University Medical Centre+, PO box 616, Maastricht, 6200 MD, The Netherlands.
Wesley J H HermansDepartment of Human Biology, NUTRIM Institute of Nutrition and Translational Research in Metabolism, Department of Human Biology, Maastricht University Medical Centre+, PO box 616, Maastricht, 6200 MD, The Netherlands.
Ines WarnkeHuman Nutrition and Care (HNC) Innovation, R&D and Regulatory, dsm-firmenich, Kaiseraugst, AG, Switzerland.
Alex OvermanDepartment of Human Biology, NUTRIM Institute of Nutrition and Translational Research in Metabolism, Department of Human Biology, Maastricht University Medical Centre+, PO box 616, Maastricht, 6200 MD, The Netherlands.
Janneau M X van KranenburgDepartment of Human Biology, NUTRIM Institute of Nutrition and Translational Research in Metabolism, Department of Human Biology, Maastricht University Medical Centre+, PO box 616, Maastricht, 6200 MD, The Netherlands.
Joan M SendenDepartment of Human Biology, NUTRIM Institute of Nutrition and Translational Research in Metabolism, Department of Human Biology, Maastricht University Medical Centre+, PO box 616, Maastricht, 6200 MD, The Netherlands.
Lex B VerdijkDepartment of Human Biology, NUTRIM Institute of Nutrition and Translational Research in Metabolism, Department of Human Biology, Maastricht University Medical Centre+, PO box 616, Maastricht, 6200 MD, The Netherlands.
Luc J C van LoonDepartment of Human Biology, NUTRIM Institute of Nutrition and Translational Research in Metabolism, Department of Human Biology, Maastricht University Medical Centre+, PO box 616, Maastricht, 6200 MD, The Netherlands. l.vanloon@maastrichtuniversity.nl.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Canola protein is a rapeseed-derived protein that contains all essential amino acids in proportions that meet the WHO amino acid scoring requirements, making it an interesting protein for human food applications. It is currently unknown whether canola protein processing modulates postprandial plasma amino acid bioavailability in vivo in humans. This study compared postprandial plasma amino acid profiles following the ingestion of unprocessed (native) canola, processed canola, and whey protein isolate in healthy, young, females. In a randomized, clinical, cross-over design, 15 healthy young females (25 ± 3 y) participated in four test days on which they consumed 20 g protein as either native canola, enzyme processed or heat processed canola protein, or 20 g whey protein. Blood samples were collected for 5 h following protein ingestion to assess plasma amino acid concentrations. Ingestion of native canola protein resulted in lower increases in plasma total amino acid (TAA) concentrations compared to whey protein (3191 ± 794 vs. 4429 ± 84 µmol∙L

Indexed as

Amino AcidsPostprandial PeriodAdultBrassica rapaCross-Over StudiesFemaleFood HandlingHumansWhey ProteinsYoung AdultAmino AcidsWhey ProteinsBioavailabilityPlant-derived proteinProtein processing

Identifiers

PMID41107640
PMCPMC12534268

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.