Evidence map›Paper›PMID 41107623›Full record

ReviewDermatology and therapy2026

Cardiovascular Disease and Psoriasis.

Małgorzata Ponikowska, Loreena Hill, Christopher S Lee, Michela Barisone, Piotr Ponikowski, Heba M Aldossary, Maria Jędrzejczyk, Grzegorz Kubielas, Izabella Uchmanowicz

Abstract readReview
In one paragraph

Review in Dermatology and therapy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Małgorzata PonikowskaUniversity Centre of General Dermatology and Oncodermatology, Faculty of Medicine, Wroclaw Medical University, Wroclaw, Poland.ORCID http://orcid.org/0000-0003-0679-676X
Loreena HillSchool of Nursing and Paramedic Science, Ulster University, Londonderry, UK.ORCID http://orcid.org/0000-0001-5232-0936
Christopher S LeeBoston College William F. Connell School of Nursing, Chestnut Hill, MA, USA.ORCID http://orcid.org/0000-0002-2510-4071
Michela BarisoneClinical Epidemiology and Research Center, IRCCS Humanitas Research Hospital, Pieve Emanuele, MI, Italy.ORCID http://orcid.org/0000-0003-4224-8779
Piotr PonikowskiInstitute of Heart Diseases, University Hospital of Wroclaw Medical University, Wroclaw, Poland.ORCID http://orcid.org/0000-0002-3391-7064
Heba M AldossaryDepartment of Nursing, Prince Sultan Military College of Health Sciences, Dhahran, Saudi Arabia. heba@psmchs.edu.sa.ORCID http://orcid.org/0000-0001-8842-6169
Maria JędrzejczykDivision of Research Methodology, Department of Nursing, Faculty of Nursing and Midwifery, Wroclaw Medical University, Wroclaw, Poland.ORCID http://orcid.org/0000-0002-7208-3509
Grzegorz KubielasDepartment of Health Care Organization, Department of Nursing, Faculty of Nursing and Midwifery, Wroclaw Medical University, Wroclaw, Poland.ORCID http://orcid.org/0000-0003-1229-0650
Izabella UchmanowiczDivision of Research Methodology, Department of Nursing, Faculty of Nursing and Midwifery, Wroclaw Medical University, Wroclaw, Poland.ORCID http://orcid.org/0000-0001-5452-0210

Funding

Uniwersytet Medyczny im. Piastów Slaskich we Wroclawiu SUBZ.L010.25.053
6 · The paper itself

Abstract

Psoriasis is a chronic inflammatory skin disease characterized by well-demarcated erythematous plaques with silvery scales that affects 2-3% of the global population. Beyond its dermatological manifestations, psoriasis has recently been recognised as a significant cardiovascular risk factor, patients with psoriasis have an approximately 50% increased relative risk of major cardiovascular events compared with the general population. This review examines the complex relationship between psoriasis and cardiovascular disease, exploring the epidemiological evidence, underlying pathophysiological mechanisms, clinical implications and therapeutic considerations. The inflammatory milieu characteristic of psoriasis, involving T cell activation, cytokine dysregulation and systemic inflammation, creates a pro-atherogenic environment that accelerates cardiovascular disease development. Understanding the mechanisms of cardiovascular risk is crucial for clinicians managing psoriatic patients, as it necessitates comprehensive risk assessment and preventive strategies beyond traditional dermatological care.

Indexed as

AtherosclerosisCardiovascular diseaseCytokinesInflammationPsoriasisRisk factors

Identifiers

PMID41107623
PMCPMC12873013

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.