SynthesisPediatric surgery international2025
Laparoscopic versus open splenectomy in non-traumatic pediatric patients: a systematic review and meta-analysis.
Synthesis in Pediatric surgery international, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed.
- Retrospective evaluation of anatomical laparoscopic single-port partial splenectomy guided by three-dimensional CT reconstruction planning for hereditary spherocytosis.Surgical endoscopy · 2026Article
- Pediatric laparoscopic splenectomy using a repurposed sterile diathermy pouch as a retrieval bag: preliminary experience.BMC surgery · 2026Article
Corrections and comments
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Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundLaparoscopic splenectomy (LS) is the preferred surgical approach for pediatric patients requiring splenectomy, though gaps remain regarding spleen size impact on outcomes and conversion rates, especially in children with hematologic disorders.
methodsA comprehensive literature search was conducted across PubMed, Medline, CINAHL, Embase, and Cochrane Library, from inception to January 2025, following PRISMA guidelines and registered with PROSPERO (CRD42025644989). Statistical analysis was performed using a random-effects model.
resultsThe initial search yielded 216 studies, 19 studies with 1898 pediatric patients included. Of those, 1202 underwent LS and 696 open splenectomy (OS). LS was associated with shorter hospital stay (MD: -1.59 days, 95% CI: -2.18 to -1.00, P < 0.00001), faster initiation of oral feeding (MD: -0.68 days, 95% CI: -1.07 to -0.29, P = 0.0006), fewer transfusions (OR = 0.38, 95% CI: 0.23 to 0.62, P = 0.0001), and conversion to OS in 2.7% of cases. OS showed shorter operative time (MD: 60.4 min, 95% CI: 37.4 to 83.4, P < 0.00001), and improved accessory spleen removal (OR: 1.91, 95% Cl: 1.02 to 3.57, P = 0.04).
conclusionOur findings support LS as a safe and effective technique in pediatric hematologic patients and provide updated evidence to guide surgical decision-making.
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