ReviewJournal of materials science. Materials in medicine2025
A review of cytotoxicity testing methods and in vitro study of biodegradable Mg-1%Sn-2%HA composite by elution method.
Review in Journal of materials science. Materials in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed.
- Freeze-Thaw-Induced Hybrid Porous PVA/PEG Hydrogels with Dynamic Load-Dissipation Capability for Cartilage Substitutes.Gels (Basel, Switzerland) · 2026Article
- Investigation of the Effects of Saffron on Neuroprotection and Circadian Rhythm in anPharmaceuticals (Basel, Switzerland) · 2026Article
- Article
- Biocompatibility of Direct 3D-Printed Clear Aligner Resins: A Comparative In Vitro Cytotoxicity Analysis.Journal of clinical and experimental dentistry · 2026Review
- Data-driven multiscale design of composite biomaterials: Integrating experiments, imaging, and computational modeling for biomedical engineering.Materials today. Bio · 2026Review
- Evaluation of the Cytotoxic Effects of Adhesive Systems with Different pH Values on L929 Fibroblast Cells: An In Vitro Study.Bioengineering (Basel, Switzerland) · 2026Article
- Oxidative Stress, Pro-Inflammatory Response, Cytotoxicity and Apoptosis Induced by Contemporary Endodontic Sealers in Human Periodontal Ligament Fibroblasts.Journal of functional biomaterials · 2026Article
- Dialdehyde Alginate as a Crosslinker for Chitosan/Starch Films: Toward Biocompatible and Antioxidant Wound Dressing Materials.International journal of molecular sciences · 2026Article
- Formulation of hispidulin-loaded sodium carboxymethyl cellulose nanoparticles: characterisation, biological activities and molecular insights.Frontiers in pharmacology · 2026Article
- Drug Delivery Device Design and Compatibility with Nitrogen Dioxide Gas Sterilization.Pharmaceuticals (Basel, Switzerland) · 2025Article
- ExoOrb: A novel visual and analytical system for therapeutic extracellular vesicles metrics.Computational and structural biotechnology journal · 2025Article
- Personalized Orbital Fracture Repair: Enhancing 3D-Printed Titanium Mesh with Biomimetic 3D-Printed HAP-COL Frameworks.Romanian journal of ophthalmologyArticle
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In recent years, magnesium alloys and their composites, a new generation of biodegradable metals, have become biomedical materials for orthopedic bone implants because of their adequate strength and high biocompatibility. Good biocompatible material should lead to low cytotoxicity, hemolysis, bleeding, and inflammation and must not be at risk for carcinogenic reactions. The medical equipment was tested for cell growth, reproduction, and morphology using in vitro tissue cells in the cytotoxicity test. This research examines the cytotoxicity of a Mg-1%Sn-2%HA composite, produced using powder metallurgy methods, utilizing an in vitro mammalian cell culture system in accordance with ISO 10993-5 criteria. Extracts were generated utilizing the elution technique in Dulbecco's Modified Eagle Medium (DMEM) supplemented with fetal bovine serum (FBS) and evaluated on L-929 mouse fibroblast cells. The cells were cultured at 37 °C with 5% CO
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.