ArticleCommunications biology2025
Midgut microbiota diversity and interactions shift when field Aedes aegypti mosquitoes carry the wMel strain of Wolbachia pipientis.
Article in Communications biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Crop: The Black Box of Mosquito Vector Fitness.Insects · 2026Review
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Authors and funding
5 authors.
Funding
Abstract
The gut microbiota plays a crucial role in mosquito biology and immunity, but the effects of Wolbachia on microbiota diversity remain unclear. In Brazil, wMel-carrying Aedes aegypti were first deployed in 2015 to replace wild populations and block arbovirus transmission. We analyzed through 16S rRNA amplicon-sequencing (V3-V4 region) the midgut microbiota of field-caught wMel- and wMel + Ae. aegypti from areas of Rio de Janeiro with different wMel invasion status. Overall, wMel+ mosquitoes exhibited reduced bacterial diversity and altered microbiota composition. The interactions between bacterial taxa were also reduced in wMel+ when compared to sympatric wMel- mosquitoes from areas with partial Wolbachia introgression, suggesting a transitional microbial composition, whereas areas with full Wolbachia invasion displayed more homogeneous, densely connected bacterial communities. Although Wolbachia played a central role in microbial networks, its effects appeared contingent on other co-occurring taxa. Notably, certain bacteria such as Acetobacteraceae (Asaia), Moraxellaceae (Acinetobacter), and Xanthomonadaceae were associated with reduced wMel abundance, potentially impacting its pathogen-blocking efficiency. Targeting these interactions may enhance the success of Wolbachia-based vector control strategies.
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