Evidence map›Paper›PMID 41107508›Full record

Trial reportArchives of gynecology and obstetrics2025

Effects of an enhanced recovery after surgery (ERAS) program in elder patients undergoing transvaginal reconstructive surgery for pelvic organ prolapse (POP): a multicenter randomized parallel open-label controlled trial.

Yueyue Yan, Yuelun Zhang, Liqun Wang, Zhijun Xia, Li Hong, Qingkai Wu, Lubin Liu, Chunfang Ha, Zhijing Sun, Juan Chen and 9 more

Abstract readRandomized Controlled TrialMulticenter Study
In one paragraph

Trial report in Archives of gynecology and obstetrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Yueyue YanDepartment of Obstetrics and Gynecology, National Clinical Research Center for Obstetric and Gynecologic Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 1 ShuaiFuyuan Road, Dongcheng District, Beijing, 100730, People's Republic of China.
Yuelun ZhangInstitute of Clinical Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100730, People's Republic of China.
Liqun WangJiangxi Maternal and Child Health Hospital, Nanchang, Jiangxi Province, China.
Zhijun XiaDepartment of Obstetrics and Gynecology, Shengjing Hospital of China Medical University, Shenyang City, Liaoning Province, China.
Li HongRenmin Hospital of Wuhan University, Hubei, China.
Qingkai WuDepartment of Obstetrics and Gynecology, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, 600 Yishan Road, Shanghai, 200233, China.
Lubin LiuDepartment of Obstetrics and Gynecology, Women and Children's Hospital of Chongqing Medical University, Chongqing, People's Republic of China.
Chunfang HaGynecology Department, General Hospital of Ningxia Medical University, Yinchuan, Ningxia, China.
Zhijing SunDepartment of Obstetrics and Gynecology, National Clinical Research Center for Obstetric and Gynecologic Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 1 ShuaiFuyuan Road, Dongcheng District, Beijing, 100730, People's Republic of China.
Juan ChenDepartment of Obstetrics and Gynecology, National Clinical Research Center for Obstetric and Gynecologic Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 1 ShuaiFuyuan Road, Dongcheng District, Beijing, 100730, People's Republic of China.
Honghui ShiDepartment of Obstetrics and Gynecology, National Clinical Research Center for Obstetric and Gynecologic Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 1 ShuaiFuyuan Road, Dongcheng District, Beijing, 100730, People's Republic of China.
Jiangyan ZhouJiangxi Maternal and Child Health Hospital, Nanchang, Jiangxi Province, China.
Hainan XuDepartment of Obstetrics and Gynecology, Shengjing Hospital of China Medical University, Shenyang City, Liaoning Province, China.
Shasha HongRenmin Hospital of Wuhan University, Hubei, China.
Zhuowei XueDepartment of Obstetrics and Gynecology, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, 600 Yishan Road, Shanghai, 200233, China.
Shentao LuDepartment of Obstetrics and Gynecology, Women and Children's Hospital of Chongqing Medical University, Chongqing, People's Republic of China.
Min LiGynecology Department, General Hospital of Ningxia Medical University, Yinchuan, Ningxia, China.
Shuo LiangDepartment of Obstetrics and Gynecology, National Clinical Research Center for Obstetric and Gynecologic Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 1 ShuaiFuyuan Road, Dongcheng District, Beijing, 100730, People's Republic of China. leahleung@foxmail.com.
Lan ZhuDepartment of Obstetrics and Gynecology, National Clinical Research Center for Obstetric and Gynecologic Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 1 ShuaiFuyuan Road, Dongcheng District, Beijing, 100730, People's Republic of China. zhu_julie@vip.sina.com.

Funding

National Key Research and Development Program of China 2021YFC2701302National Key Research and Development Program of China 2023YFC2706001
6 · The paper itself

Abstract

purposeTo develop a locally tailored ERAS program for 60-80-year-old patients with pelvic organ prolapse (POP) undergoing transvaginal mesh (TVM) surgery in low- and middle-resource countries.

methodsIn this multicenter randomized controlled trial conducted at seven tertiary hospitals, 262 women aged 60-80 scheduled for elective TVM surgery were randomly allocated (1:1) to receive either a comprehensive ERAS perioperative intervention or conventional perioperative management (131 participants per group). The primary outcomes were postoperative length of stay, pain scores, time to first flatus, removal of urinary catheter, first assisted walking, postoperative complications, readmission, emergency visit, in-hospital costs, PGI-I, QoR-15, PONV, and residual urine volume.

resultsERAS group had significantly shorter postoperative length of stay (median 3.92 days vs. 4.99 days, HR = 1.42, 95% CI 1.11-1.82, P = 0.005), lower pain scores within 24 h, faster time to first flatus, removal of urinary catheter, and first assisted walking. There were no significant differences between the ERAS and conventional groups regarding postoperative complications, readmission, emergency visit, in-hospital costs, PGI-I, QoR-15, PONV, and residual urine volume. There was no 30-day postoperative readmission in both groups.

conclusionsERAS program can reduce length of stay and improve postoperative outcomes in patients undergoing vaginal reconstructive surgery. Recommend implementing ERAS for 60-80-year-olds in East Asia where TVM surgeries are still an option for POP. CLINICAL REGISTRATION: ChiCTR2200057422 (March 12, 2022).

Indexed as

Enhanced Recovery After SurgeryGynecologic Surgical ProceduresPelvic Organ ProlapsePlastic Surgery ProceduresAgedAged, 80 and overFemaleHumansLength of StayMiddle AgedPatient ReadmissionPostoperative ComplicationsSurgical MeshTreatment OutcomeVaginaEnhanced recovery after surgeryPelvic floor reconstructive surgeryPerioperative managementTransvaginal mesh

Identifiers

PMID41107508
PMCPMC12705774

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.