Evidence map›Paper›PMID 41107502›Full record

ArticleArchives of gynecology and obstetrics2025

Clinical characterization of endometriosis phenotypes.

Louisa Hofbeck, Katharina Au, Simon Blum, Nadezda Sipulina, Laura Lotz, Johannes H Lermann, Stefan P Renner, Peter A Fasching, Matthias W Beckmann, Stefanie Burghaus

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Article in Archives of gynecology and obstetrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Louisa HofbeckDepartment of Gynecology and Obstetrics, Erlangen University Hospital, Universitäts-Endometriosezentrum Franken, Friedrich-Alexander-Universität Erlangen-Nürnberg, Universitätsstr. 21-23, 91054, Erlangen, Germany. louisa.hofbeck@uk-erlangen.de.
Katharina AuDepartment of Gynecology and Obstetrics, Erlangen University Hospital, Universitäts-Endometriosezentrum Franken, Friedrich-Alexander-Universität Erlangen-Nürnberg, Universitätsstr. 21-23, 91054, Erlangen, Germany.
Simon BlumDepartment of Gynecology and Obstetrics, Erlangen University Hospital, Universitäts-Endometriosezentrum Franken, Friedrich-Alexander-Universität Erlangen-Nürnberg, Universitätsstr. 21-23, 91054, Erlangen, Germany.
Nadezda SipulinaDepartment of Gynecology and Obstetrics, Erlangen University Hospital, Universitäts-Endometriosezentrum Franken, Friedrich-Alexander-Universität Erlangen-Nürnberg, Universitätsstr. 21-23, 91054, Erlangen, Germany.
Laura LotzDepartment of Gynecology and Obstetrics, Erlangen University Hospital, Universitäts-Endometriosezentrum Franken, Friedrich-Alexander-Universität Erlangen-Nürnberg, Universitätsstr. 21-23, 91054, Erlangen, Germany.
Johannes H LermannDepartment of Gynecology and Obstetrics, Hospital Klagenfurt, Klagenfurt, Austria.
Stefan P RennerDepartment of Gynecology and Obstetrics, Boeblingen Clinic, Hospital Sindelfingen-Böblingen, Böblingen, Germany.
Peter A FaschingDepartment of Gynecology and Obstetrics, Erlangen University Hospital, Universitäts-Endometriosezentrum Franken, Friedrich-Alexander-Universität Erlangen-Nürnberg, Universitätsstr. 21-23, 91054, Erlangen, Germany.
Matthias W BeckmannDepartment of Gynecology and Obstetrics, Erlangen University Hospital, Universitäts-Endometriosezentrum Franken, Friedrich-Alexander-Universität Erlangen-Nürnberg, Universitätsstr. 21-23, 91054, Erlangen, Germany.
Stefanie BurghausDepartment of Gynecology and Obstetrics, Erlangen University Hospital, Universitäts-Endometriosezentrum Franken, Friedrich-Alexander-Universität Erlangen-Nürnberg, Universitätsstr. 21-23, 91054, Erlangen, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeEndometriosis appears in various forms and symptoms. With regard to the established endometriosis classifications, it is hardly possible to draw conclusions from the endometriosis to the symptoms caused by it. The objective of this study was to evaluate whether different endometriosis phenotypes are associated with distinct pain profiles. MATERIALS AND

methods3329 patients underwent surgical treatment for endometriosis at the University Endometriosis Center Franconia of the Erlangen University between September 2011 and January 2024. They were grouped by phenotype [superficial (SE), deep (DIE) and adenomyosis (AM)] and assessed for pelvic pain, dyspareunia, dysuria and dyschezia. The study examined pain distribution across phenotypes and pain intensity among symptomatic patients (NRS > 0).

resultsPatients with SE only reported pelvic pain less frequently and with lower intensity than those with additional AM Groups SE/AM and SE/DIE/AM. Dyspareunia was less common in Group SE only vs. Group SE/AM; pain intensity was highest in AM only and lowest in Group SE/DIE. Dysuria was most frequent in Group SE/DIE/AM, with no significant intensity differences. Dyschezia was more frequent in Group SE/DIE/AM and less in Group SE only, again without significant intensity differences.

conclusionPain frequency and intensity differed by endometriosis phenotype. SE showed the lowest pain frequency and pelvic pain intensity. AM, especially with other subtypes, was linked to higher frequency and intensity of pelvic pain, as well as more dyspareunia and dysuria. DIE was mainly associated with more frequent dyschezia, but not with increased pelvic pain intensity.

Indexed as

EndometriosisPelvic PainAdenomyosisAdultConstipationDyspareuniaDysuriaFemaleHumansMiddle AgedPain MeasurementPhenotypeAdenomyosisClassificationDyscheziaEndometriosisPelvic painSymptoms

Identifiers

PMID41107502
PMCPMC12705834

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.