Evidence map›Paper›PMID 41107445›Full record

ArticleScientific reports2025

A performance analysis of convolutional autoencoder modified WaveGAN architectures for realistic 12 lead electrocardiogram synthesis.

Jiaqi Liu, Kwok Tai Chui, Lap-Kei Lee, Kenneth Lo, Aimin Yang, Edmond King Sing Fong

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Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

6 authors.

Jiaqi LiuSchool of Science and Technology, Hong Kong Metropolitan University, Ho Man Tin, Kowloon, Hong Kong SAR, China.
Kwok Tai ChuiSchool of Science and Technology, Hong Kong Metropolitan University, Ho Man Tin, Kowloon, Hong Kong SAR, China. jktchui@hkmu.edu.hk.
Lap-Kei LeeSchool of Science and Technology, Hong Kong Metropolitan University, Ho Man Tin, Kowloon, Hong Kong SAR, China.
Kenneth LoDepartment of Food Science and Nutrition, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong SAR, China.
Aimin YangDepartment of Medicine and Therapeutics, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong SAR, China.
Edmond King Sing FongSchool of Science and Technology, Hong Kong Metropolitan University, Ho Man Tin, Kowloon, Hong Kong SAR, China.

Funding

Hong Kong Metropolitan University RIF/2021/05
6 · The paper itself

Abstract

The burgeoning necessity for copious and diverse electrocardiogram (ECG) datasets for deep learning applications in clinical diagnostics has been impeded by the confidential nature of patient data. Related works have shown the effectiveness of additional data generation in enhancing the deep learning models' performance. This research study introduces a novel Convolutional Autoencoder-WaveGAN (CAE-WaveGAN) technique for generating synthetic but realistic 12-lead ECG images to address data scarcity. The proposed model leverages a convolutional autoencoder for efficient feature extraction from ECG signals, which is then utilized by a WaveGAN generator to synthesize high-fidelity ECG images. The method provides a practical solution for expanding ECG training datasets where patient privacy constraints and data scarcity limit the development of robust deep learning models for cardiovascular diagnosis. We conducted a comprehensive performance analysis of various CAE-WaveGAN configurations through an ablation study on the CODE-15% dataset. Experimental results demonstrate that CAE-WaveGAN achieves superior performance across all evaluation metrics, with 19.8% improvement in PSNR and 59.3% enhancement in SSIM compared to baseline methods. Our findings from the ablation study reveal that the optimal CAE-WaveGAN architecture significantly surpasses the traditional WaveGAN in terms of stability and loss metrics, offering a promising solution for generating realistic ECG data in clinical machine learning applications.

Indexed as

Deep LearningElectrocardiographyAlgorithmsAutoencoderHumansNeural Networks, ComputerSignal Processing, Computer-Assisted12-Lead ECG synthesisConvolutional autoencoderDeep learningECG data generationFeature extractionGenerative adversarial networks

Identifiers

PMID41107445
PMCPMC12534510

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.