ReviewHypertension research : official journal of the Japanese Society of Hypertension2025
Ikigai in aging hearts: Japan's approach to cardiovascular care.
Review in Hypertension research : official journal of the Japanese Society of Hypertension, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Discontinuation of Heart Failure Pharmacotherapy in Older Adults With Frailty.Journal of the American Heart Association · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The global population is aging rapidly, creating a growing demand for cardiovascular care that is better aligned with the complex comorbidities and diverse life contexts of older adults. The 5Ms of geriatrics-Mind, Mobility, Medications, Multicomplexity, and What Matters Most-provide a practical framework to individualize treatment strategies based on functional status, comorbidities, and patient values (ikigai). This review explores how integrating the 5Ms into the management of hypertension, atrial fibrillation, and heart failure can guide clinical decision-making in aging societies. We highlight practical strategies, such as deprescribing, fall risk assessment, and shared decision-making, that tailor care to patient priorities. Furthermore, we discuss policy implications, including the need for greater incentives for comprehensive geriatric assessments and advance care planning. Since evidence-based guidelines may not fully capture the complexity of older patients, incorporating the 5Ms and comprehensive assessments can support patient-centered care and help build evidence based on meaningful outcomes in aging societies. Balancing EBM and Ikigai in Aging Hearts The figure highlights how the 5Ms of geriatrics guides patient-centered decision-making. EBM evidenced based medicine.
Indexed as
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.